Notice of Special Interest (NOSI): Administrative Supplements to SEPA Awards to Develop Innovative Educational Resources to Address SARS-CoV-2 Vaccine Hesitancy
Notice Number:

Key Dates

Release Date:

March 10, 2021

First Available Due Date:
April 30, 2021
Expiration Date:
May 01, 2021

Related Announcements

PA-20-272 - Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)

Issued by

National Institute of General Medical Sciences (NIGMS)


The National Institute of General Medical Sciences (NIGMS) announces the availability of administrative supplements for the Science Education Partnership Award (SEPA) (R25) grantees to develop educational resources to address SARS-CoV-2 vaccine hesitancy.


Vaccinating the US population with SARS-CoV-2 vaccines is the key to control the spread of SARS-CoV-2 in the nation. However, a significant number of Americans, including those in medically underserved communities, have questions about vaccination. The goal of this NOSI is to support SEPA grantees in the development of SARS-CoV-2 resources, specifically related to the educational interventions of their SEPA projects, that will address key issues related to vaccine hesitancy and increase vaccine acceptance in the US.

Research Objectives

Applications must aim to develop innovative educational resources to increase vaccine confidence and encourage vaccine acceptance of the public, especially among populations with a high level of vaccine hesitancy. Examples of appropriate projects include, but are not limited to:

  • Educational resources, including interactive digital media, designed to disseminate scientific findings about SARS-CoV-2 and SARS-CoV-2 vaccines with the goals of reducing vaccine misinformation and vaccine hesitancy.
  • Public service announcements, documentaries, films, radio, TV, and other media-based community health literacy resources to support science-based reporting of SARS-CoV-2 and SARS-CoV-2 vaccines with the goals of increasing community’s participation in COVID-19 vaccination programs.

Proposed project should be an expansion of the project currently supported by the parent SEPA award. The project must not constitute a change in scope of the parent award.

Partnering with other SEPA projects as well as with other NIGMS programs, such as Institutional Development Award (IDeA) and Native American Research Centers for Health (NARCH), is encouraged. Of particular interest are educational programs that focus on reaching out to medically underserved and rural populations.

Application and Submission Information

The parent award must be active when the supplement application is submitted (e.g. within the originally reviewed and approved project period), regardless of the time remaining on the current project. SEPA projects that are currently in a no-cost extension period are not eligible to apply for this administrative supplement funding opportunity.

Applications in response to this NOSI must be submitted to PA-20-272 "Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)".

All instructions in the SF424 (R&R) Application Guide and PA-20-272 must be followed, with the following additions:

  • Application Due Date(s) – April 30, 2021 by 5:00 PM local time of applicant organization.
  • For funding consideration, applicants must include “NOT-GM-21-032” (without quotation marks) in the Agency Routing Identifier field (box 4B) of the SF424 R&R form. Applications without this information in box 4B will not be considered for this initiative.
  • Only electronic submissions will be accepted for this funding opportunity. Use one of the methods described in PA-20-272. Paper submissions and applications submitted as email attachments will be rejected without review.
  • Application budgets are limited to no more than $50,000 in direct costs, plus applicable F&A, and must be reasonable and justifiable for the proposed Administrative Supplement project.
    • As part of the budget justification, include a brief statement regarding the current available unobligated grant funds and expenditure plans, in order to demonstrate the need for the additional funds.
    • Supplements may provide support above the established dollar limit for the parent grant award.
    • Requests may be for one year of support only.
  • The Research Strategy section of the application is limited to 6 pages. Applications must describe: (1) a logic model for the proposed SARS-CoV-2 education plan as well as specific details on validated evaluation tools to be used for both short- and long-term outcomes and (2) a dissemination plan that is appropriate to the target audiences accessible Limited English Proficient Persons (LEP) persons. Applicants should discuss plans for: (1) posters, presentations, workshops, and other dissemination practices at local, regional, and national conferences and (2) the use of social media tools such as Twitter/Twiducate, Wikispaces Classroom, Skype or YouTube.

Applications that are not responsive to the terms of this NOSI, will not be considered for this initiative.

Applicants are strongly encouraged to notify one of the program contacts listed below when a request has been submitted in response to this NOSI in order to facilitate efficient processing of the request.


Please direct all inquiries to:

Tony Beck, Ph.D.
National Institute of General Medical Sciences (NIGMS)

Behrous Davani, Ph.D.
National Institute of General Medical Sciences (NIGMS)

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