Notice of Intent to Publish a Funding Opportunity Announcement for the Maximizing Investigators' Research Award Program

Notice Number: NOT-GM-19-006

Key Dates

Release Date: December 19, 2018
Estimated Publication Date of Funding Opportunity Announcement: June 03, 2019
First Estimated Application Due Date: January 17, 2020
Earliest Estimated Award Date: January 01, 2021
Earliest Estimated Start Date: January 01, 2021

Related Announcements

Issued by
National Institute of General Medical Sciences (NIGMS)


The purpose of this Notice is to inform the biomedical research community that NIGMS is planning to issue a funding opportunity announcement (FOA) to continue theMaximizing Investigators Research Award (MIRA) (R35) program. The FOA is intended for (1) new applications from eligible NIGMS-supported investigators, (2) renewal applications from current NIGMS established investigator R35 recipients, and (3) renewal applications from current NIGMS early stage investigator (ESI) R35 recipients.

This Notice is being provided to allow potential applicants sufficient time to develop responsive projects.

The FOA is expected to be published in Summer 2019 with an expected first application due date in January 2020.

This FOA will utilize the R35 activity code. Details of the planned FOA are provided below.

Research Initiative Details

An NIGMS MIRA is intended to provide support for the NIGMS-related research in an investigator's laboratory. Hence, investigators receiving a MIRA will be required to relinquish their other NIGMS research grants, with limited exceptions as noted in PAR-17-094. MIRA applications will be reviewed by broadly-based review panels within the Center for Scientific Review. Because of the disparity in career stage of PIs renewing an ESI-MIRA and established PIs renewing a MIRA, NIGMS intends for the applications of PIs who have had five or fewer years of R35 or R01-equivalent grant support to be clustered during peer review.

With the reissuance of the MIRA FOA, NIGMS intends to increase the window of eligibility to apply for a MIRA accordingly: 1) a PI may submit a MIRA application up to 24 months after the original project end date of his/her NIGMS R01 equivalent award; or 2) a PI may submit a MIRA application up to 24 months in advance of the original project end date of the R01 equivalent. When an early MIRA application is selected for funding, the start date of the MIRA award will not be delayed and current NIGMS-funding will be merged into the MIRA. When determining the window for eligibility, an R01 equivalent award may not be in an extension phase beyond the original project end date.

Funding Information

Estimated Total Funding Not Applicable
Expected Number of Awards Not Applicable
Estimated Award Ceiling Not Applicable
Primary CFDA Numbers 93.859

Anticipated Eligible Organizations

Public/State Controlled Institution of Higher Education
Private Institution of Higher Education
Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education)
Nonprofit without 501(c)(3) IRS Status (Other than Institution of Higher Education)
Small Business
For-Profit Organization (Other than Small Business)
State Government
Indian/Native American Tribal Government (Federally Recognized)
County governments
City or township governments
Special district governments
Independent school districts
Public housing authorities/Indian housing authorities
Indian/Native American Tribally Designated Organization (Native American tribal organizations (other than Federally recognized tribal governments)
U.S. Territory or Possession
Indian/Native American Tribal Government (Other than Federally Recognized)
Regional Organization

Applications are not being solicited at this time.


Please direct all inquiries to:

Zhongzhen Nie, Ph.D.
National Institute of General Medical Sciences (NIGMS)
Telephone: 301-594-3827

Vernon Anderson, Ph.D.
National Institute of General Medical Sciences (NIGMS)
Telephone: 301-594-3827

Weekly TOC for this Announcement
NIH Funding Opportunities and Notices