Request for Information: Input to the National Eye Institute Strategic Plan Draft Document
Notice Number:

Key Dates

Release Date:

May 19, 2021

Response Date:
June 07, 2021

Related Announcements

NOT-EY-20-002 - Request for Information: Input to the National Eye Institute Strategic Plan: 2020 Vision for the Future

Issued by

National Eye Institute (NEI)


The National Eye Institute (NEI) is finalizing its Strategic Plan under the auspices of the National Advisory Eye Council (NAEC). This Notice is a time-sensitive Request for Information (RFI) seeking feedback from the public on the NEI Strategic Plan draft document, describing the needs, gaps, and opportunities for vision research over the next five years.


Charged to protect and preserve the eyes and vision of the American people, NEI supports basic and clinical research that unravels the mysteries of how vision works at a fundamental level and provides patients with new therapies and standards of care that maintain and improve quality of life.

The new NEI Strategic Plan seeks to distill those reflections into a cohesive document that will guide efforts to address those gaps and opportunities over the next five years. NEI has always been—and will continue to be—committed to high quality investigator-initiated research and will fund the best science across the broad spectrum of vision research. Ultimately, NEI stakeholders provide the catalyst for identifying and implementing the goals.

NEI has been incorporating broad public and expert input in the development of this plan, starting in the winter of 2019-2020 with an initial Request for Information (RFI). This public comment period engaged perspectives from scientists, clinicians, patients, vision advocates, and the public. NEI received a robust response to the RFI, which informed the selection and agendas of expert panels for seven cross-cutting areas of emphasis during the spring and summer of 2020. NEI incorporated the topics covered in the RFI and panels into the planning document and presented the information publicly before the NAEC.

Under each area of emphasis, NEI provides a summary of goals related to research needs, gaps, and opportunities for the institute to address over the next five years.

Areas of Emphasis

Visual System in Health and Disease

  • From Genes to Disease Mechanisms
  • Biology and Neuroscience of Vision
  • Immune System and Eye Health

Capitalizing on Emerging Fields

  • Regenerative Medicine
  • Data Science

Preventing Vision Loss and Enhancing Well-being

  • Individual Quality of Life
  • Public Health and Disparities Research

Information Requested

This Notice invites comments from researchers in academia and industry, health care professionals, patient advocates and health advocacy organizations, scientific or professional organizations, federal agencies, and other interested members of the public on the draft NEI Strategic Plan draft document. When developing comments, please read the draft strategic plan and provide any high-level, content related feedback by submitting a written response to Organizations are strongly encouraged to submit a single response that reflects the views of their organization and membership.

Results of this RFI and updated Strategic Plan will be presented at the June 11, 2021, meeting of the NAEC and the finalized Strategic Plan will be posted on the NEI website once it is approved.


Responses to this RFI are voluntary. Please do not include any personally identifiable information or any information that you do not wish to make public. Proprietary, classified, confidential, or sensitive information should not be included in your response. The Government will use the information submitted in response to this RFI at its discretion. The Government reserves the right to use any submitted information on public websites, in reports, in summaries of the state of the science, in any possible resultant solicitation(s), grant(s), or cooperative agreement(s), or in the development of future funding opportunity announcements. This RFI is for informational and planning purposes only and is not a solicitation for applications or an obligation on the part of the Government to provide support for any ideas identified in response to it. Please note that the Government will not pay for the preparation of any information submitted or for use of that information.

NEI encourages the dissemination of this RFI opportunity to broader networks and is looking forward to receiving input from the community. Please provide a written response to by June 7, 2021.


Please direct all inquiries to:

National Eye Institute (NEI)
Office of Program Planning and Analysis

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