Notice of National Eye Institute Plans for Transition of Support for the Small Grant (R03) and Exploratory/Developmental Grant (R21) Mechanisms

Notice Number: NOT-EY-06-001

Key Dates
Release Date: March 8, 2006

Issued by
National Eye Institute, (
National Institute on Aging (NIA) , (

The NEI has terminated its use of the Small Grant (R03) mechanism, effective immediately. Investigators who wish to submit applications for small research projects that can be carried out in a short period of time with limited resources should consider using either the R01 Research Project Grant or the R21 Exploratory/Developmental Grant mechanism.

The long-standing NEI Small Research Grants for Data Analysis (R03) program, previously announced as PAR-03-019,, will be reissued as an R21 Exploratory/Developmental grant program. This change will be announced in the NIH Guide to Grants and Contracts and in the FIND portion of in time for transition to use of the SF424 (R&R) form for the June 1, 2006 receipt date. The NEI will continue to support investigator-initiated R21 applications under the NIH Omnibus Solicitation, PA-06-181,


For information about this Notice, please contact any NEI Program Director at 301-451-2020, or

Ellen S. Liberman, Ph.D., M.B.A.
Director, Lens and Cataract/Glaucoma and Optic Neuropathies Programs
Division of Extramural Research
National Eye Institute
Suite 1300, 5635 Fishers Lane
Bethesda, MD 20892-9300

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