ADMINISTRATIVE SUPPLEMENTS FOR TECHNOLOGY ENHANCEMENT IN NEI-FUNDED LABORATORIES Release Date: August 29, 2001 NOTICE: NOT-EY-02-001 National Eye Institute The NEI is announcing the availability of administrative supplements to NEI- funded research projects (R01, R29, R37, U01, U10) for the development and expansion of technological capabilities that will enhance ongoing research. This announcement provides information regarding application procedures, submission deadlines, and review criteria. PURPOSE The purpose of these supplements is to introduce innovative technologies and/or to upgrade existing facilities that support NEI-funded research projects. Requests are limited to the purchase of equipment, supplies, and technical personnel essential to facilities that are relevant to a critical number of NEI-supported projects. Examples of requests that will be considered under this supplement program include, but are not limited to: updating protein sequencing technology, enhancing bioinformatics capacity, introducing state of the art imaging technology, upgrading proteomics tools, and establishing transgenic mouse facilities. It is expected that the applicant institutions will support the establishment and operation of the facility and provide future year support. This administrative supplement program is issued in response to recommendations developed by the National Advisory Eye Council. Information regarding NEI programmatic interests is available in NEI"s publication, Vision Research, A National Plan: 1999-2003 , which is located at http://www.nei.nih.gov/resources/strategicplans/plan.htm. ELIGIBILITY All requests must meet the following criteria: (1) the project period of the grant to be supplemented must have at least two years remaining at the time of award and (2) the work proposed must be within the scope of the research originally recommended by peer-review for the grant to be supplemented. NEI will give priority to administrative supplement requests that will benefit at least three NEI-funded research project grants (R01, R29, R37, U01, U10). BUDGET INFORMATION Applicants may request up to two years of support. The requested budget for the first year should be between $100,000 and $400,000 direct costs. The second year budget should not exceed $100,000 direct costs. HOW TO APPLY This is a one-time announcement with requests submitted on or before February 1, 2002. The following must be included in the application: o A description of the NEI-funded research projects that will benefit from the presence of this technology/facility, including how the technology will enhance ongoing research projects within the scope of the originally proposed specific aims. o Documentation of strong institutional commitment to the facility. Applicants must describe the resources and environment available at the institution to effectively operate the facility, including support for personnel, equipment, supplies, and availability of laboratory space. o A plan for continued support for the facility and the technology after the time period of the supplement. o A detailed budget and budget justification for the personnel, equipment, and supplies requested. o A description of the administration and management of the facility. Important consideration should be given to setting priorities for the facility and ensuring access by the vision researchers. A request for an administrative supplement under this program should include a cover letter requesting the administrative supplement and identifying this program. The application should be developed using the PHS Form 398 (revised 5/01) Face Page, budget Form Pages 4 and 5, Biosketch of the Principal Investigator, and resources Form Page 8. The Research Plan should address the five points described above and should not exceed five pages. One copy of the request should be sent to: Ellen S. Liberman, Ph.D. Director, Lens and Cataract and Glaucoma Programs National Eye Institute Executive Plaza South, Suite 350 6120 Executive Blvd, MSC 7164 Bethesda, MD 20892-7164 Rockville, MD 20852 (for express/courier service) REVIEW PROCEDURE A committee composed of NIH extramural staff will evaluate the request for the administrative supplement. Awards will be determined on the basis of scientific merit, program relevance, and the availability of funds. The expected award date is June 1, 2002. Funded applicants will be expected to provide a progress report based on the administrative supplement as part of the regular progress report of the parent grant. INQUIRIES Inquiries concerning this notice are strongly encouraged. The opportunity to clarify any issue or questions from potential applicant is welcome. Direct inquiries regarding programmatic issues to: Ellen S. Liberman, Ph.D. Director, Lens and Cataract and Glaucoma Programs National Eye Institute Executive Plaza South, Suite 350 6120 Executive Blvd, MSC 7164 Bethesda, MD 20892-7164 Telephone: (301) 496-0484 FAX: (301) 402-0528 Email: ellenliberman@nei.nih.gov Direct fiscal inquiries to: William W. Darby Grants Management Branch, NEI National Eye Institute Executive Plaza South, Suite 350 6120 Executive Blvd, MSC 7164 Bethesda, MD 20892-7164 Telephone: (301) 496-5884 FAX: (301) 496-9997 Email: wwd@nei.nih.gov


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