The purpose of this Notice is to highlight NIEHS' interest in accepting Administrative Supplements to active research projects related to exposures and health outcomes as a consequence of Hurricane Harvey that made landfall in August 2017. The unprecedented and widespread damage caused by Hurricane Harvey was substantial. The consequences of exposures to biological (such as mold, biotoxins from harmful algal blooms) and chemical hazards, as well as social stressors (e.g., displacement, social isolation, racial/ethnic and cultural factors) on the short-term and longer-term health effects on impacted communities is of concern. Therefore, the ultimate goal of this Notice is to better understand the longer-term consequences of Hurricane Harvey through continued follow-up of affected populations and the impact on the environmental quality as time has passed. These studies can include currently funded NIEHS projects focused on Hurricane Harvey as well as NIEHS grants funded to study a population in the Hurricane Harvey impacted area and for which there is the ability to conduct ancillary studies. Proposed projects must be within scope of the parent grant. However, proposals that build off initial findings would be considered in scope.

Examples of topics of interest include:

• Resiliency of communities and individuals in the aftermath of Hurricane Harvey
• Effect of multiple stressors on Hurricane Harvey impacted populations (this could include role of continued natural and technological events on communities)
• Physical and mental health consequences of Hurricane Harvey over time
• Characterization of changes in environmental quality and human exposures spatially and temporally (i.e., have the affected areas returned to baseline or is there a new normal to consider for future events)

Description of circumstances for which administrative supplements are available.

Application and Submission Information

Applications for this initiative must be submitted using the following opportunity or its subsequent reissued equivalent.

• PA-18-591 - Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)

All instructions in the SF424 (R&R) Application Guide and PA-18-591 must be followed, with the following additions:

• Application Due Date(s) May 1, 2020, by 5:00 PM local time of applicant organization
• For funding consideration, applicants must include “NOT-ES-20-012” (without quotation marks) in the Agency Routing Identifier field (box 4B) of the SF424 R&R form. Applications without this information in box 4B will not be considered for this initiative.
• The Research Strategy section of the application is limited to 6 pages.
• All NIEHS supported mechanisms are eligible to apply (e.g., R01, R21, P30, P42, etc.).
• T?he process for Streamlined Submissions using the eRA Commons cannot be used for this initiative.
• Applicants are strongly encouraged to notify their program contact of the parent award that a request has been submitted in response to this FOA in order to facilitate efficient processing of the request

Eligibility: Administrative supplements are limited to parent awards issued by NIEHS that are conducting Hurricane Harvey-related research or are studying a population in the Hurricane Harvey impacted area and for which there is the ability to conduct ancillary studies to understand the effects of Hurricane Harvey on the study population. The parent grant must still be active.

Award Budget: Total Direct Costs for a supplement application cannot exceed $500,000.

NIEHS will conduct administrative reviews of all supplement applications based on an initial review by the Program Officer assigned the parent grant.

Administrative Evaluation Criteria:

• Is the parent award progressing satisfactorily/according to planned timeline and milestones?
• Is the work proposed feasible and advancing our understanding of the effects of Hurricane Harvey?