Notice of Intent to Publish a Funding Opportunity Announcement for Children’s Health Exposure Analysis Resource: Exposure Data Repository and Resource for Statistical Analysis and Methods Development (U2C)

Notice Number: NOT-ES-15-009

Key Dates
Release Date: February 10, 2015  

Estimated Publication Date of Announcement: March 2015  
First Estimated Application Due Date: April 2015  
Earliest Estimated Award Date: September 2015  
Earliest Estimated Start Date: September 2015

Related Announcements
NOT-ES-15-007
NOT-ES-15-010

Issued by
National Institute of Environmental Health Sciences (NIEHS)

Purpose

The National Institute of Environmental Health Sciences (NIEHS) intends to promote the integration of environmental factors into studies of children’s health by publishing three distinct but integrated Funding Opportunity Announcements (FOA) that solicit applications in support of a Children’s Health Exposure Analysis Resource (CHEAR).  CHEAR focuses specifically on providing access to infrastructure for comprehensive exposure analysis to existing epidemiological cohort studies involving research into children’s health. 

Exposures measured by CHEAR will encompass the breadth of the exposome, the totality of biological, psycho-social, chemical and physical exposures through the use of both targeted and non-targeted methods of analysis.  The program will also include the characterization of associated biological response indicators to provide additional information on exposures and their mechanistic effects.  CHEAR will provide standardized analysis of samples and data as well as a data repository.  This will enable an integration of exposure analysis across studies to integrate the combined contributions of multiple environmental factors as determinants of children’s health across a range of diseases and disorders. 

The FOAs are intended for release in March 2015 with an expected application due date in late Spring 2015.

The FOA will utilize the U2C activity codes.  Details of the planned FOA are provided below.

Research Initiative Details

The CHEAR Exposure Data Repository and Resource for Statistical Analysis and Methods Development (UC2) will provide comprehensive consulting and support for the analysis and interpretation of comprehensive children’s health data generated within and outside the network. Applicants should have expertise in the development and application of statistical methodologies and informatics tools to analyze and integrate the diverse set of data generated and enhance the capabilities of the network.

This resource will also require significant data science expertise in order to develop and maintain an accessible repository for all data generated within the network.  The database should include tools to support broad sharing, analysis, and interoperability of exposure data with data generated within and outside the network. To accomplish this, a central task will be leading a community-based process for developing and implementing data and metadata standards for exposures.

This Resource will interact with other CHEAR components.

APPLICATIONS ARE NOT BEING SOLICITED AT THIS TIME.

Inquiries

Please direct all inquiries to:

David M. Balshaw, PhD
National Institute of Environmental Health Sciences (NIEHS)
Telephone: 919-541-2448
Email: Balshaw@nih.gov

Claudia Thompson, PhD
National Institute of Environmental Health Sciences (NIEHS)
Telephone: 919-541-4638
Email:  Claudia.Thompson@nih.gov