RESEQUENCING OF MOUSE GENOME, RFP NIH-ES-04-02

RELEASE DATE:  January 16, 2004

NOTICE:  NOT-ES-04-003

National Institute of Environmental Health Sciences (NIEHS)
 (http://www.niehs.nih.gov)

The purpose of this notice is to announce a request for proposal 
(RFP NIH-ES-04-02) (http://www.niehs.nih.gov/dert/rcb/rfp.htm ). The 
National Institute of Environmental Health Sciences (NIEHS) is 
soliciting proposals for resequencing of genome mouse strains.  The 
overall objective of this requirement is to identify the DNA sequence of 
the nuclear genomes of 15 commonly used strains of inbred laboratory 
mice and which sequence determines the genetic basis of trait 
differences between the different inbred mouse strains.  In so doing, 
the contractor shall develop a publicly available, easily accessible, 
annotated database.  Specifically, the contractor shall determine the 
identify of each base in each position along each mouse chromosome and 
develop and maintain an annotated record of the sequence data obtained 
for each of 15 different inbred mouse strains.  The contract is expected 
to cover a three-year performance period with two one-year options.  The 
contract will be a cost reimbursement, level of effort type contract.  
It is anticipated that approximately 13,520 labor hours will be required 
each contract year.  The anticipated release date of the request for 
proposal is February 2, 2004 with proposals due March 18, 2004.  
Interested firms should fax a request for RFP NIH-ES-04-02 to the 
attention of Ms. Jo Ann Lewis, Contracting Officer at (919) 541-2712 or 
send an e-mail request to lewisj@niehs.nih.gov.  The electronic version 
of the FedBizOps synopsis will be available on the Internet at: 
http://www.niehs.nih.gov/dert/rcb/rfp.htm.  An electronic copy of the 
RFP (without all attachments) will be posted to this site on or about 
February 2, 2004.  This requirement in unrestricted.  NAICS Code is 
541710.

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