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NIH Guide: NATIONAL CENTER FOR TOXICOGENOMICS MICROARRAY RESOURCE
NATIONAL CENTER FOR TOXICOGENOMICS MICROARRAY RESOURCE

Release Date:  September 6, 2001

NOTICE:  NOT-ES-02-002

National Institute of Environmental Health Sciences

NIH-ES-01-18

The National Institute of Environmental Health Sciences (NIEHS) is
soliciting proposals for the purpose of (1) providing gene expression
platforms and protocols for acquiring high quality gene expression
data from chemical treated biological systems (Task 1), and (2)
providing a gene expression profile database containing analysis and
data mining tools (Task 2).   In addition, there may be up to four (4)
optional studies per year encompassing up to a total of 2400 purified
RNA samples (Task 1).   Specifically, the Contractor shall establish a
gene expression platform that demonstrates utility and validity
through data generation and exchange with the NIEHS Microarray Center
(NMC); develop standards and practices for incorporation of data from
NIEHS extramurally supported consortia; conduct gene expression
analysis; develop a database management system; implement a robust
data mining tools and public access to store information, computed
data and integrated public domain biological resources; and host,
maintain, update and secure the database system.  Offeror may propose
either or both Tasks.  One or more awards are anticipated with an
award date of August 1, 2002.  The period of performance is expected
to be five (5) years.  For estimating purposes the Government
estimates the level-of-effort as follows: Gene Analysis Capabilities
(Task 1): 13,832 direct labor hours per year as Senior Professional -
832 direct labor hours (i.e., Principal Investigator, bioinformatics
leader); Other Professionals - 12,480 direct labor hours (i.e.,
laboratory technician, computer technician),  Administrative Support -
520 direct labor hours.  The Prototype Microarray Gene Expression
Database System (Task 2): 15,080 direct labor hours per year as Senior
Professional - 2,080 direct labor hours (i.e., Principal
Investigator/Bioinformatics, information technology systems leader);
Other Professionals - 12,480 direct labor hours (i.e., computer
technician); and Administrative Support - 520 direct labor hours.
Optional Studies: 13,832 direct labor hours as Senior Professional -
832 direct labor hours (i.e., Principal Investigator/Bioinformatics
leader); Other Professionals - 12,480 direct labor hours (i.e.,
laboratory technician, computer technician); and Administrative
Support - 520 direct labor hours.  The anticipated release date of the
RFP is September 24, 2001 with proposals due January 8, 2002.
Interested firms should telefax a request for RFP NIH-ES-01-18 to the
attention of Ms. Melissa Gentry, Procurement Technician at (919)
541-2712 or send an e-mail request to gentry1@niehs.nih.gov.  The
electronic version of the CBD synopsis is available on the Internet at
http://www.niehs.nih.gov/dert/rcb/rfp.htm.  An electronic copy of the
RFP will be posted to this site on or about September 24, 2001.  This
requirement is unrestricted.  NAICS is 541710.


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