STUDIES TO EVALUATE THE TOXICOLOGIC AND CARCINOGENIC POTENTIAL OF SAN TRIMER IN LABORATORY ANIMALS FOR THE NATIONAL TOXICOLOGY PROGRAM Release Date: July 12, 2001 NOTICE: NOT-ES-01-010 RFP NIH-ES-01-15 National Institute of Environmental Health Sciences The NIEHS is soliciting offers for a contract to evaluate the toxicologic and carcinogenic potential of SAN-Trimer. The base contract (designated as Phase 1) shall consist of work activities associated with the determination of bulk chemical analysis (identity and purity) and validation of dose formulation and analysis procedures. Upon successful completion of Phase 1, the Government may unilaterally exercise options for the conduct of 7-week, 18-week, and 2-year studies specified as Phases 2 through 4, respectively. These studies shall be conducted according to the Specifications for the Conduct of Studies to Evaluate the Toxic and Carcinogenic Potential of Chemical, Biological and Physical Agents in Laboratory Animals for the National Toxicology Program dated September 2000. Offerors shall have a working laboratory in place by the date of proposal submission. The Principal Investigator, Toxicologist, Chemist, Veterinarian, Health and Safety Officer and Quality Assurance Unit Officer shall be employees of the contract laboratory (i.e., not consultants or subcontractors). The daily interaction and constant coordination of efforts needed amongst these discipline areas throughout the in-life portion of the studies makes it critical that they be physically and organizationally together. Award of one cost-reimbursement, completion type contract on April 30, 2002 on an open competition basis is contemplated as a result of this solicitation. The estimated level of effort is 320 labor hours for the base contract and 25,425 labor hours for all options. The estimated period of performance is approximately four months for the base contract and four years eight months if all options are exercised. Interested organizations should telefax a request for RFP NIH-ES-01-15 to the attention of Ms. Melissa Gentry, Procurement Technician at (919) 541-2712 or send an e-mail request to gentry1@niehs.nih.gov. The electronic version of the CBD synopsis is available on the Internet at: http://www.niehs.nih.gov/dert/rcb/rfp.htm. An electronic copy of the RFP (without the NTP Specifications) will be posted to this site on or about July 24, 2001. All responsible sources may submit a proposal which shall be considered by the Agency. Expected release date of the RFP is July 24, 2001 with proposals due September 21, 2001. This requirement is unrestricted. NAICS Code is 541710. Requests should reference RFP NIH-ES-01-15 and be forwarded to: National Institute of Environmental Health Sciences Research Contracts Branch, DERT ATTN: Ms. Jackie Osgood, Contracting Officer 79 T.W. Alexander Drive, 4401 Building P. O. Box 12874 Research Triangle Park, NC 27709
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