August 16, 2023
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Eye Institute (NEI)
National Institute on Aging (NIA)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Center for Complementary and Integrative Health (NCCIH)
All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers. The following NIH Offices may co-fund applications assigned to those Institutes/Centers.
Office of Behavioral and Social Sciences Research (OBSSR)
This Notice of Special Interest (NOSI) announces the availability of administrative supplements to support the dissemination of promising technologies and resources generated from active Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative awards, where funds necessary for dissemination efforts (e.g., establishing new collaborations between innovators and end users) were not anticipated and included in the original research plan, or additional funds for dissemination efforts are needed.
The BRAIN Initiative is aimed at revolutionizing our understanding of the human brain. By accelerating the development and application of innovative technologies and resources, researchers will be able to produce a new dynamic picture of the brain that, for the first time, shows how individual cells and complex neural circuits interact in both time and space. It is expected that the application of these new technologies and resources will ultimately lead to new ways to treat, cure, and even prevent brain disorders.
The NIH is one of several federal agencies involved in the BRAIN Initiative. Planning for the NIH component of the BRAIN Initiative is guided by the long-term scientific plan, "BRAIN 2025: A Scientific Vision," which details seven high-priority research areas and calls for a sustained federal commitment of $4.5 billion over 12 years and "The BRAIN Initiative 2.0: From Cells to Circuits, Toward Cures," which was released in 2019 and provides an assessment of achievements as well as details for new priority areas for investment. This NOSI and other Notices of Funding Opportunities (NOFOs) issued in Fiscal Year 2020 and beyond are based on careful considerations of the recommendations of the BRAIN 2025 and BRAIN 2.0 reports and input from the NIH BRAIN Multi-Council Working Group. Videocasts of the NIH BRAIN Multi-Council Working Group meetings are available at http://www.braininitiative.nih.gov/about/mcwg.htm. This NOSI specifically responds to the BRAIN 2.0 reports call for strategic investment to facilitate rapid, effective, and collaborative dissemination of resources to unlock the full impact of the BRAIN Initiative.
The NIH encourages BRAIN Initiative applications from groups that are underrepresented in the biomedical, behavioral, or clinical research workforce (see data at http://www.nsf.gov/statistics/showpub.cfm?TopID=2&SubID=27 and the most recent report on Women, Minorities, and Persons with Disabilities in Science and Engineering). Such individuals include those from underrepresented racial and ethnic groups, those with disabilities, and those from disadvantaged backgrounds.
Additionally, the BRAIN Initiative encourages researchers to partner with and consider dissemination to investigators from institutions eligible for NIH Research Enhancement Awards such as the Research Enhancement Award Program (REAP), Academic Research Enhancement Awards (AREA), or Institute Development Awards (IDeA), where the aggregate amount of NIH funding has historically been low.
This NOSI provides supplemental funding for BRAIN Initiative-supported projects focused on developing and/or testing new technologies and resources, where user testing will increase the potential impact of the project by providing valuable information about the functionality, utility, effectiveness, etc. of the technology or resource, but funds necessary for such efforts were not anticipated and included in the original budget, or additional funds for dissemination efforts are needed. This NOSI will support small dissemination efforts for which a clear value to the identified user group is demonstrated in the application. The proposed work must be within the scope of the original project of the eligible parent award and involve dissemination plans not included in the parent application.
Projects may accomplish this goal by engaging in at least one of the following types of activities. This list is representative, but not exhaustive:
Proposed techniques, resources, or approaches must be at a stage wherein the potential for a broader impact on research has been identified. To that end, applicants must include information about the laboratories/users to whom they plan to disseminate the resource, including the protocols that users are expected to execute. The number of users identified should be appropriate for the type of resource being disseminated and the stage of development but should be greater than one person/laboratory.
The below list are examples of activities that are NOT responsive to this NOSI. Applicants considering such efforts are encouraged to explore alternative funding mechanisms.
Proposals may include dissemination to users who are not funded by the BRAIN Initiative , as well as other BRAIN recipients. Applicants are encouraged to consider the importance of diversity in the context of their dissemination efforts such as collaborating with investigators/institutions that are eligible for REAP or AREA grants or are located in IDeA-eligible states.
Projects proposing the dissemination of technologies/resources with commercial potential (i.e., SBIR/STTR grants) are allowed, but the projects funded under this supplement should provide the end users with the technology or resource at no cost. Marketing, advertising, and sales costs are not allowed. For all submissions, a clear value to the intended user group must be demonstrated in the application.
The Research Strategy section must not exceed 6 pages. The Research Strategy should include the following information:
Recipients should receive feedback directly from end users yearly, at a minimum, and include this feedback as an attachment in their Research Performance Progress Report (RPPR) of the parent award to the NIH.
Application and Submission Information
Applications for this initiative must be submitted using the following opportunity or its subsequent reissued equivalent.
PA-20-272 - Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
|Application Acceptance Periods
|September 18, 2023 – November 30, 2023
|December 1, 2023 – February 28, 2024
|March 1, 2024 – May 31, 2024
|June 1, 2024 – August 31, 2024
Submissions are due by 5:00 PM local time of applicant organization.
Proposals submitted in response to this NOSI will be reviewed by the BRAIN Initiative Dissemination Team. Preference will be given to applications that address support of training or dissemination to diverse collaborators (For example, REAP, AREA, or IDeA grant eligible institutions).
In addition to the general criteria listed in PA-20-272 (or the subsequent reissue), supplement applications responding to this NOSI will be evaluated using the following criteria:
For any scientific, research-related, or eligibility questions on this administrative supplement notice, please contact the program officer listed on the most recent Notice of Award of the parent award.
For all other questions, please contact:
BRAIN Initiative Dissemination Program