Notice of Intent to Publish a Funding Opportunity Announcement for Point-of-Care Technologies Research Network Centers (U54 Clinical Trial Optional)
Notice Number:

Key Dates

Release Date:
May 10, 2022
Estimated Publication Date of Funding Opportunity Announcement:
July 25, 2022
First Estimated Application Due Date:
September 26, 2022
Earliest Estimated Award Date:
July 20, 2023
Earliest Estimated Start Date:
July 27, 2023
Related Announcements

NOT-EB-23-001 - Notice of Technical Assistance Webinar for NOT-EB-22-001 - Notice of Special Interest (NOSI): Small Business Initiatives for Innovative Diagnostic Technology for Improving Outcomes for Maternal Health

NOT-TW-22-002 - Notice of Information that the Fogarty International Center (FIC) is participating in NOT-EB-22-001, "Notice of Intent to Publish a Funding Opportunity Announcement for Point-of-Care Technologies Research Network Centers (U54 Clinical Trial Optional).

PAR-17-453 - Point-of-Care Technologies Research Network Centers (U54)

NOT-DA-22-069 - Notice of NIDA's Participation in NOT-EB-22-001

Issued by

National Institute of Biomedical Imaging and Bioengineering (NIBIB)

National Heart, Lung and Blood Institute (NHLBI)


The National Institute for Biomedical Imaging and Bioengineering intends to reissue PAR-17-453, Point-of-Care Technologies Research Network (POCTRN), with additional partnering NIH Institutes and Centers. The purpose of this funding opportunity announcement is to solicit Technology Research and Development Center (TRDC) applications for the POCTRN. POCTRN’s purpose is to drive the development and application of innovative point of care, home-based, improved clinical laboratory tests and testing technologies. The POCTRN TRDCs will merge scientific and technological capabilities with clinical need to address unmet testing, monitoring, and treatment areas.

The network of POCTRN TRDCs will have broad expertise across many research areas and will cover multiple levels of technology readiness from proof of feasibility through products and procedures used in clinical practice (The FOA will include participating NIH Institute/Center Areas of Interest).

The scope of work covered within each Center will include, but are not limited to:

  • Sub-project awards to support point-of-care technology development activities led by investigators
  • Assessment and communication of unmet clinical needs in point-of-care testing
  • Collaborations with physical scientists, computational scientists, and engineers (as well as researchers from other relevant disciplines, as appropriate) on technology development projects
  • Development of external partnerships (e.g., technology, clinical, industry, and regulatory) necessary to move enabling technologies toward clinical applications
  • Validation and clinical testing of prototype point-of-care devices
  • Creation of training opportunities for technology developers and other stakeholders on clinical issues related to the development of point-of-care devices.

The FOA will utilize the U54 activity code and is expected to be published in June 2022 with an expected application due date in Fall 2022. This opportunity is open to all applicants, including the existing POCTRN grantees as well as new applicants.

For more information about the POCTRN visit

Research Initiative Details
Funding Information


Estimated Total Funding


Expected Number of Awards
Estimated Award Ceiling


Primary Assistance Listing Number(s)


Anticipated Eligible Organizations
Public/State Controlled Institution of Higher Education
Private Institution of Higher Education
Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education)
Small Business
For-Profit Organization (Other than Small Business)
State Government
Indian/Native American Tribal Government (Federally Recognized)
County governments
Independent school districts
Public housing authorities/Indian housing authorities
Indian/Native American Tribally Designated Organization (Native American tribal organizations (other than Federally recognized tribal governments)
U.S. Territory or Possession
Indian/Native American Tribal Government (Other than Federally Recognized)
Non-domestic (non-U.S.) Entity (Foreign Organization)
Regional Organization
Eligible Agencies of the Federal Government

Applications are not being solicited at this time.


Please direct all inquiries to:

Tiffani Bailey Lash, PhD

National Institute of Biomedical Imaging and Bioengineering (NIBIB)