Notice Number: NOT-EB-18-020

Key Dates
Release Date: June 11, 2018

Issued by
National Institute of Biomedical Imaging and Bioengineering (NIBIB)

Purpose

The National Institute of Biomedical Imaging and Bioengineering (NIBIB) announces an opportunity for NIBIB-supported investigators to request administrative supplements to stimulate personalized imaging technology development. Efforts supported by these supplements must be focused on technologies developed within the parent grant.

Imaging devices are often designed non-specifically to accommodate as many subjects as possible. However, incorporating subject specificities into the operation may significantly enhance the detectability of the underlining abnormality. This Administrative Supplement is to stimulate the development of personalized imaging devices incorporating subject-specific information via advanced engineering technologies such as additive manufacturing, stretchable electronic circuits, or low-cost high-performance computing hardware. Investigators are encouraged to study the feasibility, costs, and benefits of adapting their imaging/detection technologies in a personalized manner. Potential outputs from the supplement activity may include a prototype of personalized imaging hardware that demonstrates feasibility and cost-effectiveness or the preliminary demonstration of improved performance of imaging methodology by incorporating subject-specific information.

The following are representative, but non-exclusive, examples of potential administrative supplements:

• Demonstration of the feasibility, costs, and benefits of adapting MRI, PET, or MEG detector geometry or array layout to the anatomy of specific subjects.
• Demonstration of the feasibility, costs, and benefits of radio-frequency transmission or the emission of other energy sources in a real-time and subject-specific manner for improved safety or enhanced efficacy.
• Achieving closed-loop operation by incorporating subject’s anatomy or biomarkers into a real-time, low-cost first-principle model-based control system.

Administrative supplement requests should be submitted to PA-18-591, Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional) https://grants.nih.gov/grants/guide/pa-files/PA-18-591.html.

Applicants should begin their Research Strategy by stating: "This application is being submitted in response to NOT-EB-18-020".

Supplements up to $100,000 direct costs for up to 12 months will be considered for research grants, career awards, non-center cooperative agreements and training grants. Supplements up to $200,000 direct costs for up to 12 months will be considered for research center grants or research center cooperative agreements. The project and budget periods of the supplement request must be within the currently approved project period for the existing parent award.

These administrative supplements are available to meet increased costs that are within the scientific scope of the parent grant but were unforeseen when the grant application was submitted. Applicants are strongly encouraged to discuss the aims of the proposed work with the NIBIB program officer assigned to the parent grant to assess suitability for this funding opportunity.

Requests must be received by July 24, 2018.

Inquiries

Please direct all inquiries to:

Shumin Wang, Ph.D.
National Institute of Biomedical Imaging and Bio-Engineering (NIBIB)
Telephone: 301-594-9001
Email: [email protected]