Notice of Update for PAR-10-141, Transforming Biomedicine at the Interface of the Life and Physical Sciences (R01), and PAR-10-142, New Biomedical Frontiers at the Interface of the Life and Physical Sciences (R01)

Notice Number: NOT-EB-11-004

Key Dates
Release Date: March 10, 2011

Related Notices
PAR-10-141: Transforming Biomedicine at the Interface of the Life and Physical Sciences
PAR-10-142: New Biomedical Frontiers at the Interface of the Life and Physical Sciences

Issued by
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of General Medical Sciences (NIGMS)


This Notice is being issued as an update to PAR-10-141 and PAR-10-142 (, published in the NIH Guide on March 18, 2010, to:

  1. Clarify the research objectives for NIBIB and NIGMS.
  2. Note that all applicants are required to address the NSF Broader Impact Statement (NSF Review Criteria).
  3. Describe submission format for NSF Broader Impact Statement.

Clarification of NIBIB and NIGMS Research Objectives in Section I. Funding Opportunity Description
1. Research Objectives

Applications should clearly address what new line of investigation will be pursued at the interface, the extent of the innovation, and the relevance to the mission of one of the participating institutes.

The NIBIB is committed to integrating the physical and engineering sciences with the life sciences to advance basic research and medical care.  Areas that are most appropriate for funding by NIBIB and will be considered for funding are: new biomedical imaging and bioengineering techniques which will improve health; new devices which fundamentally improve the detection, treatment, and prevention of disease; novel and innovative enhancements to existing imaging and bioengineering modalities which improve health; new technologies for early disease detection and assessment of health status; and development of innovative advanced imaging and engineering techniques for conducting biomedical research at multiple scales.

The NIGMS encourages applications in the core areas of ( cell biology, biophysics, genetics, developmental biology, pharmacology, physiology, biological chemistry, computational social science, and computational science.

The objectives of NIAMS and NSF are detailed in the FOAs.

Applicants focusing on specific disease or domain not aligned with the mission of the participating institutes on these FOAs should contact the NIH Institute or Center to find FOAs that are more appropriate to their research interest.

Clarification of NSF Review Criteria in Section IV. Application and Submission Information
2. Content and Form of Application Submission


Broad Impact Statement
The NSF Broader Impact Statement, should be placed into the SF424 (R&R) Other Project Information Component.  Provide this information in a separate file, attaching it as Item 12, Other Attachments.  In the body of the text, begin the section with a heading indicating “NSF Broader Impact.” When saving this file, name it “NSF Broader Impact.” This statement, addressing the broad impact review criteria, is limited to 3 pages.

This policy applies to all new, renewal, revision, or resubmission applications. All other aspects of this FOA remain unchanged.

6. Other Submission Requirements

NSF Review Criteria

All applicants are now required to include the NSF Review Criteria (Broader Impact Statement) in their applications.

Applications omitting the Broader Impact Statement will be considered incomplete and will not undergo peer review.


Please direct all inquiries to:

Richard Conroy, Ph.D.
National Institute of Biomedical Imaging and Bioengineering
National Institutes of Health
Democracy Plaza II (DEMII), Suite 200
6707 Democracy Blvd.
Bethesda, MD 20892-5477
TEL 301-402-1486
FAX 301-480-4973

Weekly TOC for this Announcement
NIH Funding Opportunities and Notices

Office of Extramural Research (OER) - Home Page Office of Extramural
Research (OER)
  National Institutes of Health (NIH) - Home Page National Institutes of Health (NIH)
9000 Rockville Pike
Bethesda, Maryland 20892
  Department of Health and Human Services (HHS) - Home Page Department of Health
and Human Services (HHS) - Government Made Easy

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