Notice Number:NOT-DK-14-019
Key Dates
Release Date:
May 23, 2014
RFA-DK-14-012
Issued by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Purpose
This Notice corrects the language in the Funding Opportunity Description and the Research Strategy section of the PHS 398 Research Plan for the Administrative Core to remove all references to a clinical element within RFA-DK-14-012: Silvio O. Conte Digestive Diseases Research Core Centers (P30).
Part 2. Full Text of Announcement
Section I. Funding Opportunity Description
The section currently reads:
Clinical Element or Clinical Component
Since the NIDDK is interested in translating work supported by the DDRCCs into practical therapies for digestive and liver diseases, the clinical element or Clinical Component can serve as a resource, a focal point, and a facilitator for this function. Investigators, therefore, need not be funded directly for clinical studies to use the services or expertise nor to justify the existence of this unit. Providing the capability for translating basic research findings into a clinical setting is the ultimate goal of the clinical element or Clinical Component for those Centers wishing to build this part of their research base.
A clinical element may exist as a part of a Core, usually the Administrative Core. Alternatively, a separate, full-fledged Clinical Component is also an option, if the requirements for it can be met. Besides leading to a better understanding of the etiology and natural history of disease, a clinical element or Clinical Component might provide biostatistics support; help with clinical study design; foster collaboration among researchers; aid in recruitment of subjects for clinical studies; support epidemiological studies in areas of digestive and/or liver diseases; or provide modest funding for tissue, DNA, or serum storage. In addition, a Clinical element or Clinical Component may help Center members to effectively address NIH policies concerning women, children, and ethnic minority population participation in clinical studies.
The section has been modified to read:
Clinical Component
Since the NIDDK is interested in translating work supported by the DDRCCs into practical therapies for digestive and liver diseases, the Clinical Component can serve as a resource, a focal point, and a facilitator for this function. Investigators, therefore, need not be funded directly for clinical studies to use the services or expertise nor to justify the existence of this unit. Providing the capability for translating basic research findings into a clinical setting is the ultimate goal of the Clinical Component for those Centers wishing to build this part of their research base. Besides leading to a better understanding of the etiology and natural history of disease, a Clinical Component might provide biostatistics support; help with clinical study design; foster collaboration among researchers; aid in recruitment of subjects for clinical studies; support epidemiological studies in areas of digestive and/or liver diseases; or provide modest funding for tissue, DNA, or serum storage. In addition, a Clinical Component may help Center members to effectively address NIH policies concerning women, children, and ethnic minority population participation in clinical studies. Alternatively, if the requirements for a full-fledged Clinical Core, rather than a Clinical Component, can be met, a Core rather than Component may be requested.
Section IV. 2. Content and Form of Application Submission
PHS 398 Research Plan (Administrative Core)
Research Strategy
This section currently reads:
Research Strategy: The Administrative Core is key to the coordination and functioning of the Center. Therefore, describe the administrative structure of the DDRCC, including: chain-of-command; committee structures (e.g. Internal Advisory Committee, P and F review committee, other oversight or management committees, and the required External Advisory Committee); and Core, Enrichment Program, and Clinical element (if included) management.
This section has been modified to read:
Research Strategy: The Administrative Core is key to the coordination and functioning of the Center. Therefore, describe the administrative structure of the DDRCC, including: chain-of-command; committee structures (e.g. Internal Advisory Committee, P and F review committee, other oversight or management committees, and the required External Advisory Committee); and Core and Enrichment Program management.
Inquiries
Please direct all inquiries to:
Michael Grey, PhD
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Telephone: 301-640-0121
Email: GreyMJ@mail.nih.gov
and Human Services (HHS)
