Major Affiliates to Join the Type 1 Diabetes TrialNet Clinical Network

Notice Number: NOT-DK-06-005

Key Dates
Release Date: February 2, 2006

Issued by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), (

This is to inform potential applicants that the Type 1 Diabetes TrialNet plans to expand its clinical trial network of Affiliate sites by identifying institutions that are prepared to serve the role of a Major Affiliate . Major Affiliates will provide direct TrialNet presence in communities that do not now have a Clinical Center and will serve as clinical sites (treatment and follow-up) for TrialNet studies. Major Affiliates will receive direct infrastructure funding for TrialNet activities as well as reimbursement for patient care costs via a subcontract with the George Washington University TrialNet Coordinating Center.

TrialNet is a network of medical centers aimed at studying the development, prevention and early treatment of type 1 diabetes.  TrialNet is conducting multiple clinical trials with investigators from 18 Clinical Centers in North America , Europe, and Australia.  The TrialNet Natural History Study will provide information about risk factors associated with the development of type 1 diabetes in relatives of affected individuals.  TrialNet is also performing intervention studies aimed at preservation of insulin-producing cells in individuals at risk for type 1 diabetes as well as in persons newly diagnosed with diabetes. 

Additional information on TrialNet can be found at:

Instructions for submission of request in response to the TrialNet Major Affiliate Request for Support (RFS) can be found at:

Request for Support should be addressed to:

John M. Lachin, Sc.D.
Principal Investigator, TrialNet Coordinating Center
The Biostatistics Center
The George Washington University
6110 Executive Boulevard, Suite 750
Rockville , MD 20852
Phone: (301) 881-9260

The deadline for receipt of Request for Support at The Biostatics Center of the George Washington University is close of business (5:00 PM ET) Tuesday February 21, 2006.

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