Release Date:  August 2, 2002

NOTICE:  NOT-DK-02-006 (see also NOT-DK-02-004)

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 

The purpose of this Notice is to announce that the date of submission 
of offers has been extended from August 8 to August 23, 2002, no later 
than 3:00 PM local time.  The second purpose of the Notice is to 
announce the availability of the Government's response to potential 
offerors' questions.  To obtain this information, please contact Ms. 
Mireles at the address listed below, within the original Notice (NOT-
DK-02-004).  All other aspects of the RFP remain unchanged.

The National Institute of Diabetes and Digestive and Kidney Diseases 
(NIDDK) has a requirement to set up central NIDDK facilities for 
archival storage of biosamples and data collected in large, multi-site 
studies.  In addition, there is a need for a central genetic sample 
facility to serve the needs of new studies by providing uniform high-
quality laboratory and archiving services.  Central archival 
repositories will enhance the value of large studies by increasing 
access to the biosamples and data that have been collected.  
Investigators seeking to reanalyze biosamples and/or data from NIDDK-
funded large studies will be able to direct their inquiries to a single 
central entity, rather than to numerous laboratories with individual 
storage and access policies.  Thus, when appropriate, researchers will 
be able to obtain samples and/or data expeditiously and efficiently.

Objectives:  The repositories will serve three separate functions:

1) Biosample repository - Gathering, storing, and distributing samples 
from studies.  The repository will work with investigators in new and 
ongoing studies to implement an appropriate labeling, aliquoting and 
storage system that will facilitate the transfer of the biosamples.  In 
some instances, the repository may be directed to acquire samples from 
studies already completed.

2) Data repository – Consulting with new and ongoing studies to prepare 
research data for eventual use by others.  Working with studies and 
other contractors to develop sample labeling and information exchange 
systems.  Gathering, storing and distributing the complete, finished 
datasets associated with archived biosamples from completed studies, 
and helping researchers carry out simple searches of stored datasets.  
Creating and maintaining the website for the NIDDK Central 

3) Genetics repository - Providing support services for genetics 
studies, including cell line immortalization, DNA extraction and 

Potential offerors may propose on one or more of the projects.  A 
public pre-solicitation meeting was held on November 28,2001.  A 
transcript of this meeting may be obtained at

The Request for Proposals, RFP NIH-NIDDK-02-04 was issued on May 6, 
2002 and proposals are due by 3:00 p.m., August 23, 2002.  To receive a 
copy of this RFP, please make your request in writing to Ms. Marlene 
Mireles, Contract Specialist, 6707 Democracy Boulevard, Suite 772, 
Bethesda, Maryland 20817, telephone number: 301-594-8831.  Telephone 
requests will not be honored.  This Notice does not commit the 
Government to a contract award. 

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