Notice Number: NOT-DE-17-011

Key Dates
Release Date: June 22, 2017

Issued by
National Institute of Dental and Craniofacial Research (NIDCR)

Purpose

The purpose of this Notice is to inform the applicants that effective July 17, 2017, NIDCR will no longer be participating in PA-16-040, " Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21)"

Modifications are as follows:

Participating Organization(s)
National Institutes of Health (NIH)

Components of Participating Organizations
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Cancer Institute (NCI)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Institute on Drug Abuse (NIDA)
National Institute of Neurological Disorders and Stroke (NINDS)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Part 2. Full Text of Announcement
Section I. Funding Opportunity Description

IC Specific Guidelines

NIAMS: In addition to its mission-relevant R21 projects, the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) would also like to use the R21 mechanism to stimulate and promote research in building complex 3-dimensional in vitro human musculoskeletal and skin tissue models to study developmental biology, physiology, and disease pathogenesis as well as for drug discovery and toxicity studies.  NIAMS is not interested in applications are developing 3D tissues for transplantation, or engineering non-human tissue models, or developing simple 3-D models that do not go significantly beyond those currently in use, such as human skin equivalents composed of only normal keratinocytes and fibroblasts.

NICHD: The mission of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is to ensure that every person is born healthy and wanted, that women suffer no harmful effects from reproductive processes, and that all children have the chance to achieve their full potential for healthy and productive lives, free from disease or disability, and to ensure the health, productivity, independence, and well-being of all people through optimal rehabilitation. The NICHD is interested in supporting bioengineering research that advances the development of technology and medicine to accomplish this mission. Examples of areas of research interest include, but are not limited to: a) the development of novel technologies, both imaging and non-imaging, which accelerate the ability to safely and non-invasively assess human placental development and function in real time across pregnancy; b) pediatric specific technologies and equipment used by emergency and trauma care personnel; and, c) innovations in diagnostic methods such as advanced imaging, fluid biomarkers, or genetic profiling to assess rehabilitation intervention readiness.  For additional information about specific scientific programs of research interest to a Branch in the NICHD, please visit http://www.nichd.nih.gov.

NINDS: For applications relevant to the mission (http://www.ninds.nih.gov/about_ninds/mission.htm) of the National Institute for Neurological Disorders and Stroke (NINDS): NINDS will not accept applications under this announcement that include clinical trials (https://grants.nih.gov/grants/guide/notice-files/NOT-OD-15-015.html). A clinical trial is a prospective biomedical or behavioral research study of human subjects designed to answer specific questions about safety, tolerability, efficacy and/or effectiveness of pharmacologic, behavioral, biologic, surgical, or device (invasive or non-invasive) interventions. Other human subjects research can be submitted and NINDS may decline funding of any application that includes human subjects for programmatic or administrative reasons. Applicants considering projects involving human subjects research are strongly encouraged to contact Scientific/Research staff.
Applications proposing non-clinical studies concluding in a clinical trial should be submitted to one of the following NINDS CREATE Devices FOAs specifically designed for pre-clinical and pilot clinical studies for therapeutic devices (http://www.ninds.nih.gov/funding/areas/translational_research/CREATE-Devices.htm).
Applications proposing a clinical trial must be submitted to one of the following NINDS FOAs specifically designed for clinical trials (http://www.ninds.nih.gov/research/clinical_research/index.htm#tab3-panel)

Inquiries

Please direct all inquiries to:

Nadya Lumelsky, Ph.D.
National Institute of Dental and Craniofacial Research
Telephone: 301-594-7703
Email: nadyal@nidcr.nih.gov