Revision: Participation of the National Institute of Dental and Craniofacial Research (NIDCR) in PAR-15-282 "Multidisciplinary Studies of HIV/AIDS and Aging (R21)"

Notice Number: NOT-DE-17-005

Key Dates
Release Date:  December 9, 2016

Related Announcements
PAR-15-282
This notice supersedes NOT-DE-17-001.  

Issued by
National Institute of Dental and Craniofacial Research (NIDCR)

Purpose

This Notice is to inform potential applicants that the National Institute of Dental and Craniofacial Research (NIDCR) is participating, effective with the publication of NOT-DE-17-001 on November 17, 2016, , in PAR-15-282 "Multidisciplinary Studies of HIV/AIDS and Aging (R21)". NOT-DE-17-001 inconsistently listed the activity code for this FOA and is being rescinded.

The following sections of PAR-15-282 were updated with the publication of NOT-DE-17-001 and remain modified to reflect the participation of NIDCR in this Funding Opportunity Announcement (FOA).

Part 1. Overview Information

Components of Participating Organizations

National Institute on Aging (NIA)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute on Drug Abuse (NIDA)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Institute of Dental and Craniofacial Research (NIDCR)

Catalog of Federal Domestic Assistance (CFDA) Number(s)
93.866, 93.393, 93.394, 93.395, 93.396, 93.399, 93.856, 93.846, 93.279, 93.242, 93.853, 93.837, 93.838, 93.839, 93.233, 93.273, 93.855, 93.121

Part 2. Full Text of Announcement

Section I. Funding Opportunity Description

The modification of the FOA below introduced in NOT-DE-17-001 remains:

Interests of Specific Institutes/Centers

National Institute of Dental and Craniofacial Research (NIDCR)
NIDCR is interested in research that investigates the effects of HIV infection and treatment on dental, oral soft and hard tissues, and salivary glands.  Specifically, changes in these tissues with relation to aging adults and premature aging of oral tissues in chronic and acute HIV infections are of high priority.  NIDCR does not support clinical trials through this FOA.  Studies may include but are not limited to:

  • Periodontal disease progression in the context of HIV infection and HAART.
  • Mechanisms of dental caries development and progression in HIV/AIDS-affected individuals.
  • Effects of HIV/AIDS and HAART on salivary gland infiltrates, fibrosis and xerostomia.
  • Oral mucosal pathologies and composition changes in the context of HIV/AIDS.
  • HIV infection, HAART, and their influence on developing osteonecrosis of the jaw.

Part 2. Section VII. Agency Contacts

Scientific/Research Contact(s)
Gallya Gannot, DMD, PhD
National Institute of Dental and Craniofacial Research (NIDCR)
Telephone: 301-451-5096
Email: gallya.gannot@nih.gov

Financial/Grants Management Contact(s)
Diana Rutberg, MBA
National Institute of Dental and Craniofacial Research (NIDCR)
Telephone: 301-594-4798
Email: rutbergd@mail.nih.gov

Inquiries

Please direct all inquiries to:

Gallya Gannot, DMD, PhD
National Institute of Dental and Craniofacial Research (NIDCR)
Telephone: 301-451-5096
Email: gallya.gannot@nih.gov