National Institute on Drug Abuse (NIDA)
The purpose of this Notice is to alert the community that NIH plans to publish a set of Funding Opportunity Announcements (FOAs) as part of the Helping to End Addiction Long-termSM (HEAL) Initiative to support research project sites, a Data Coordinating Center, and a Consortium Administrative Core for the HEALthy Brain and Child Development (HBCD) Study
This Notice is being provided to allow potential applicants sufficient time to form meaningful collaborations and develop responsive applications.
The primary objective of the HBCD Project is to conduct a large scale multi-site longitudinal study that can prospectively examine human brain, cognitive, behavioral, social, and emotional development beginning at birth and extending through middle childhood. The study will comprise a normative sample that represents the diversity of pregnant women in the US population, a cohort of women who have used opioids and other substances during pregnancy will also be recruited, and a comparison group from similar backgrounds/environments as the cohort of women who have used substances. The study is intended to create a well-characterized cohort of children in order to examine the developmental impact of pre/postnatal drug exposure and multiple other genetic and environmental factors that affect risk or resilience in various health and mental health domains. Anonymized data from this cohort will be made available to the broader research community during the course of the study to maximize their utility.
The FOAs are expected to be published in Fall 2020 with an expected application due date in WINTER 2021.
These FOAs will utilize the cooperative agreement (U) activity codes. Details of the planned FOAs are provided below.
This Notice encourages investigators with expertise and insights in neurodevelopment to consider applying for these new FOAs.
This project is expected to be a collaboration between researchers having wide ranging expertise. This includes expertise in areas such as: neuroimaging, neurodevelopment, cognitive and behavioral science, environmental science, gene/environment interactions, substance use, mental health, family dynamics, bioethics, data management and biostatistics; as well as recruitment and retention of vulnerable populations in long term studies.
The goal of the HBCD Project is to collect data in multiple domains to provide knowledge about the multiplicity of factors that affect a child’s health, brain, and behavioral development, an essential first step toward designing policies and interventions that promote well-being and resilience in all children. Below are some of the overarching research objectives, which are inherently interdependent and mutually informative:
It is expected that investigators, upon funding, will work together with federal staff at NIH Institutes, Centers and Offices to achieve project goals.
Applications are not being solicited at this time.
Please direct all inquiries to: