Notice of Intent to Publish a Funding Opportunity Announcement for Limited Competition Adolescent Brain Cognitive Development (ABCD) Study Funding Opportunity Announcement - Research Project Sites (U01 - Clinical Trial Not Allowed)

Notice Number: NOT-DA-18-032

Key Dates

Release Date: October 09, 2018
Estimated Publication Date of Funding Opportunity Announcement: March 01, 2019
First Estimated Application Due Date: July 01, 2019
Earliest Estimated Award Date: March 01, 2020
Earliest Estimated Start Date: April 01, 2020

Related Announcements


Issued by
National Institute on Drug Abuse (NIDA)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
National Cancer Institute (NCI)
National Institute of Mental Health (NIMH)
Office of Research on Women's Health (ORWH)


NIDA and the following NIH Institutes and Centers (ICs), NIAAA, NIMH, ORWH, and NCI intend to publish a Collaborative Research on Addiction at NIH (CRAN) funding opportunity announcement to solicit applications to renew current research project sites in service of a nationwide, multisite, multi-modal, longitudinal cohort study to prospectively examine brain and behavioral development from late childhood (approximately age 9-10) through adolescence into early adulthood. Current primary awardees will be eligible to apply and this new award period will be 7 years in duration.

The primary objective of this initiative is to design and implement a study that can collect data to address the following overarching research objectives, which are inherently interdependent and mutually informative:

  • Describe individual developmental trajectories (e.g., brain, cognitive, emotional, academic), and the factors that can affect them.
  • Develop national standards of healthy brain development.
  • Investigate the roles and interaction of genes and the environment on development.
  • Study how physical activity, sleep, screen time, sports injuries, and other experiences affect brain development.
  • Examine the factors that influence the onset, course, and severity of mental illnesses.
  • Understand the relationship between mental health and substance use.
  • Study how use of different substances (caffeine, nicotine, alcohol, marijuana) affects developmental outcomes, and vice versa.

This Notice is being provided to allow the current ABCD research project sites sufficient time to develop meaningful collaborations, identify program faculty, and create responsive applications. The FOA is expected to be published in March 2019 with an expected application due date in July 2019.

This FOA will utilize the U01 activity code. Details of the planned FOA are provided below.

Research Initiative Details

Each research project site could be a single institution, or it could be formed as a central hub institution with one other institution as a spoke to the hub. In either organizational setup, the Program Director(s)/Principal Investigator(s) will have overall responsibility.

This FOA will run in parallel with companion FOAs that solicit applications for a Coordinating Center and a Data Analysis, Informatics, and Resource Center. It is expected that investigators upon funding will work jointly with federal staff at NIH institutes to achieve study goals.

Funding Information

Estimated Total Funding TBD
Expected Number of Awards TBD
Estimated Award Ceiling TBD
Primary CFDA Numbers TBD

Anticipated Eligible Organizations

Public/State Controlled Institution of Higher Education
Private Institution of Higher Education
Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education)
Nonprofit without 501(c)(3) IRS Status (Other than Institution of Higher Education)
Small Business
For-Profit Organization (Other than Small Business)
State Government
Indian/Native American Tribal Government (Federally Recognized)
County governments
City or township governments
Special district governments
Independent school districts
Public housing authorities/Indian housing authorities
Indian/Native American Tribally Designated Organization (Native American tribal organizations (other than Federally recognized tribal governments)
U.S. Territory or Possession
Indian/Native American Tribal Government (Other than Federally Recognized)
Non-domestic (non-U.S.) Entity (Foreign Organization)
Regional Organization

Applications are not being solicited at this time.


Please direct all inquiries to:

Bethany Deeds, Ph.D.
National Institute on Drug Abuse (NIDA)