Request for Information (RFI): "Availability of Hair Samples from Individuals Who Abuse Drugs”

Notice Number: NOT-DA-16-041

Key Dates
Release Date: October 3, 2016
Response Date:  November 1, 2016  

Related Announcements
None    

Issued by
National Institute on Drug Abuse (NIDA)

Purpose

The National Institute on Drug Abuse seeks information about the availability of hair samples from individuals who abuse drugs. Of particular interest are hair samples from individuals in clinical trials where urine samples are being collected, self-report, and any other clinical history is reported  This information will be used to identify resources for the possible use in the development of MALDI-mass spectrometry Imaging of drug metabolites in hair. The MALDI mass spectrometry approach ionizes the drug metabolites at specific locations on the hair and characterizes them via mass spectrometry.  By taking a series of data points along the hair, the time course of drug use can be determined. Goals include an evaluation of how robust this approach is for a diverse population and to correlate these measurements with patient history.

Information Requested

  • Description of Study in which hair samples have been obtained in a clinical trial.
  • Number of hair samples
  • Characteristics of hair, i.e. color, curly, strait etc
  • Origin of Ancestry
  • Self-report of drug use
  • Any data from drug testing or
  • Availability of urine, blood, or saliva that could be used to measure recent drug use

How to Submit a Response

Responses will be accepted until November 1, 2016 by submitting to jpollock@mail.nih.gov.  The collected information will be analyzed and may be used to guide future US Government efforts to develop a program in the use of MALDI-mass spectrometry Imaging of drug metabolites in hair to determine the history of drug use in the past three months.

Note:  This RFI is for planning purposes only and should not be construed as a solicitation for applications or an obligation on the part of the government.  The government will not pay for the preparation of any information submitted or for the government’s use of that information.

Inquiries

Please direct all inquiries to:

Jonathan D. Pollock, Ph.D.
National Institute on Drug Abuse (NIDA)
Telephone: 301-435-1309
Email: jpollock@mail.nih.gov