Notice to Modify Instructions in RFA-DA-15-004 "NIDA Avant-Garde Award Program for HIV/AIDS and Drug Use Research (DP1)" regarding a Program Director/Principal Investigator's (PD/PI's) Accomplishments, the Biographical Sketch and the Research Strategy

Notice Number: NOT-DA-15-072

Key Dates
Release Date:  June 11, 2015

Related Announcements
RFA-DA-15-004  

Issued by
National Institute on Drug Abuse (NIDA)

Purpose

The purpose of this Notice is to modify the instructions for providing information about a Program Director/Principal Investigator's (PD/PI's) accomplishments and biographical sketch to align with the requirements for the new biographical sketch format that was effective as of May 25, 2015 (see NOT-OD-15-032).  

Current language

Part 2. Section IV.2 Instructions for Application Submission

SF424(R&R) Other Project Information

All instructions in the SF424 (R&R) Application Guide must be followed, with the following additional instructions:
Bibliography & References Cited:  Do not use.  Reference citations cannot be attached here, but may be included in the essay.
Equipment:  Do not use.
Other Attachments:  Attach a description of no more than one page of the applicant’s single most significant publication or research accomplishment. Applicants should submit one single accomplishment, not a summary of several accomplishments, multiple publications, or background narratives.  Publications or other documents will not be accepted.

Revised language

Part 2. Section IV.2 Instructions for Application Submission

SF424(R&R) Other Project Information

All instructions in the SF424 (R&R) Application Guide must be followed, with the following additional instructions:
Bibliography & References Cited:  Do not use.  Reference citations cannot be attached here, but may be included in the essay.
Equipment:  Do not use.
Other Attachments:  Do not use.

Current language

Part 2. Section IV.2 Instructions for Application Submission

SF424(R&R) Senior/Key Person Profile

All instructions in the SF424 (R&R) Application Guide must be followed, with the following additional instructions:
Profile - Project Director/Principal Investigator Field -  Attach Biographical Sketch:  Attach the biographical sketch of the PD/PI using the sample format on the Biographical Sketch Format Page shown in the Application Guide, omitting Section A (Personal Statement) and Section D (Research Support). No biographical sketches of potential collaborators or other key personnel are to be submitted and will not be accepted.

Profile - Project Director/Principal Investigator Field -  Current and Pending Support:  Attach a list of Current and Pending Support from all sources, including current year direct costs and percent effort devoted to each project. A statement must be included that, if chosen to receive an award, the applicant will commit a minimum of 35% or 4.2 person months of his/her research effort to the project supported by the Avant-Garde Award Program for HIV/AIDS Research.

Profile - Senior Key Person 1:  Do not use.  Submit information only for PD(s)/PI(s).  Information on collaborators or other key personnel is not required but may be included in the Essay.

Revised language

Part 2. Section IV.2 Instructions for Application Submission

SF424(R&R) Senior/Key Person Profile

All instructions in the SF424 (R&R) Application Guide must be followed, with the following additional instructions:

Profile - Project Director/Principal Investigator Field -  Current and Pending Support:  Attach a list of Current and Pending Support from all sources, including current year direct costs and percent effort devoted to each project.

Profile - Senior Key Person 1:  Do not use.  Submit information only for PD(s)/PI(s).  Information on collaborators or other key personnel is not required but may be included in the Essay.

Current Language

PHS 398 Research Plan

All instructions in the SF424 (R&R) Application Guide must be followed, with the following additional instructions:

Specific Aims: Do not use.

Research Strategy: Upload the Essay here. Describe the applicant’s innovative vision for, and the significance of, the HIV/AIDS biomedical or behavioral problem to be addressed, and the applicant's qualifications to engage in groundbreaking research. The essay should describe the individual's view of the major challenges in HIV/AIDS biomedical or behavioral research to which he/she can make seminal contributions. No detailed scientific plan should be provided since the research strategy is expected to evolve during the tenure of the grant. The essay should include the following sections in the order given with the headings as shown below:

Project title: The project title must be included at the beginning of the essay.

Project description: What is the scientific problem or challenge that will be addressed, and why is this important? What are the pioneering, and possibly high-risk, approaches that, if successful, might lead to groundbreaking or paradigm-shifting results and how might these results benefit substance users? If the initial strategy/approach does not work out as planned, what alternative strategies/approaches might be employed?

Evidence of innovativeness: What concrete evidence can you provide for your claim of innovativeness? For example, qualities common to many highly innovative people include an interest in, and the ability to integrate, diverse sources of information; an inclination to challenge paradigms and take intellectual risks; persistence in the face of failure; an ability to be flexible and a willingness to take a new view of a vexing problem; an ability to attract the right collaborators; and the energy and concentration necessary to plan and execute effective strategies for accomplishing goals.

How the planned research differs from your past or current work: Describe how the project represents a new and distinct direction for your research.

Compatibility with the goal of the Avant-Garde Award Program for HIV/AIDS Research: Why is the planned research uniquely suited to the stated goal of the Avant-Garde Award Program for HIV/AIDS Research, rather than a traditional grant mechanism? How will the planned research move the field forward in a truly transformative way?

Information on collaborations may be included in the essay. Literature references are not required, but, if included, must fit within the page limit. Figures and illustrations may be included but must also fit within the page limit. Do not include links to websites to provide further information. No animations (movies) are allowed in any documents.

Letters of Support: Provide letters of support from significant collaborators for the Avant-Garde Award project. 

Resource Sharing Plan: Individuals are required to comply with the instructions for the Resource Sharing Plans (Data Sharing Plan, Sharing Model Organisms, and Genome Wide Association Studies (GWAS)) as provided in the SF424 (R&R) Application Guide, with the following modification: Generally, Resource Sharing Plans (Data Sharing Plan, Sharing Model Organisms, and GWAS Sharing Plan) are expected, but for this FOA the Resource Sharing Plans will be requested as Just in Time information if an award is being considered. 

Appendix:  Do not use the Appendix to circumvent page limits. Follow all instructions for the Appendix as described in the SF424 (R&R) Application Guide. Appendix materials are not allowed and will not be accepted.

Revised language

PHS 398 Research Plan

All instructions in the SF424 (R&R) Application Guide must be followed, with the following additional instructions:

Specific Aims: Do not use.

Research Strategy: Upload the Essay here. Describe the applicant’s innovative vision for, and the significance of, the HIV/AIDS biomedical or behavioral problem to be addressed, and the applicant's qualifications to engage in groundbreaking research. The essay should describe the individual's view of the major challenges in HIV/AIDS biomedical or behavioral research to which he/she can make seminal contributions. No detailed scientific plan should be provided since the research strategy is expected to evolve during the tenure of the grant. The essay should include the following sections in the order given with the headings as shown below:

Project title: The project title must be included at the beginning of the essay.

Statement of research effort commitment: A statement must be included that, if chosen to receive an award, the applicant will commit a minimum of 35% or 4.2 person months of his/her research effort to the project supported by the Avant-Garde Award Program for HIV/AIDS Research. Applications without such a statement will be considered incomplete.

Project description: What is the scientific problem or challenge that will be addressed, and why is this important? What are the pioneering, and possibly high-risk, approaches that, if successful, might lead to groundbreaking or paradigm-shifting results and how might these results benefit substance users? If the initial strategy/approach does not work out as planned, what alternative strategies/approaches might be employed?

Evidence of innovativeness: What concrete evidence can you provide for your claim of innovativeness? For example, qualities common to many highly innovative people include an interest in, and the ability to integrate, diverse sources of information; an inclination to challenge paradigms and take intellectual risks; persistence in the face of failure; an ability to be flexible and a willingness to take a new view of a vexing problem; an ability to attract the right collaborators; and the energy and concentration necessary to plan and execute effective strategies for accomplishing goals.
How the planned research differs from your past or current work: Describe how the project represents a new and distinct direction for your research.

Compatibility with the goal of the Avant-Garde Award Program for HIV/AIDS Research: Why is the planned research uniquely suited to the stated goal of the Avant-Garde Award Program for HIV/AIDS Research, rather than a traditional grant mechanism? How will the planned research move the field forward in a truly transformative way?

Information on collaborations may be included in the essay. Literature references are not required, but, if included, must fit within the page limit. Figures and illustrations may be included but must also fit within the page limit. Do not include links to websites to provide further information. No animations (movies) are allowed in any documents.

Letters of Support: Provide letters of support from significant collaborators for the Avant-Garde Award project.  

Resource Sharing Plan: Individuals are required to comply with the instructions for the Resource Sharing Plans (Data Sharing Plan, Sharing Model Organisms, and Genome Wide Association Studies (GWAS) as provided in the SF424 (R&R) Application Guide, with the following modification: Generally, Resource Sharing Plans (Data Sharing Plan, Sharing Model Organisms, and GWAS Sharing Plan) are expected, but for this FOA the Resource Sharing Plans will be requested as Just in Time information if an award is being considered. 

Appendix:  Do not use the Appendix to circumvent page limits. Follow all instructions for the Appendix as described in the SF424 (R&R) Application Guide. Appendix materials are not allowed and will not be accepted.

All other aspects of this FOA remain the same.

Inquiries

Please direct all inquiries to:

Lynda Erinoff, Ph.D.
National Institute on Drug Abuse (NIDA)
Telephone: 301-402-1972
Email: lerinoff@nida.nih.gov