Notice of Availability of Administrative Supplements for Adolescent Substance Use Screening Tool Development and Validation for U.S. General Medical and Dental Settings

Notice Number: NOT-DA-12-002

Key Dates

Release Date: October 28, 2011  
Receipt Date: January 06, 2012 
Earliest Anticipated Start Date: March, 06, 2012 

Issued by

National Institute on Drug Abuse (NIDA)
National Institute on Dental and Craniofacial Research (NIDCR)


The National Institute on Drug Abuse, along with the National Institute on Dental and Craniofacial Research, announce an Administrative Supplement program to provide funds to supported research projects for research on adolescent substance use screening tool development and validation for U.S. general medical and dental settings.

The purpose of this Notice is to announce an administrative supplement program to support NIDA or NIDCR funded research project grants that could support research for the development and validation of tools to provide 1) a quick screen and 2) a brief assessment of substance use severity for adolescents.  The tools developed should be amenable for inclusion in an electronic health record (EHR) at U.S. based general medical and dental settings. When used together, these tools will assist the clinician provider in identifying youth who either present with a substance use disorder (SUD) or is at high risk of developing a SUD. The goal is to encourage qualified investigators to form collaborations with psychometricians, substance abuse experts, developmental pediatrician/adolescent clinician/child psychiatrist researchers and research methodologists to submit proposals that validate either newly developed or adaptations of existing tools. Research proposed under this announcement must be within the scope of the funded parent research grant.


Youth are not routinely screened for tobacco, alcohol or other substances at general medical and dental settings. Frequently cited obstacles to universal screening are that the existing screening instruments are not well-suited as they do not address time constraints or workflow issues at these settings. Ideally, screening tools must be brief, valid and reliable, demonstrate acceptable psychometric properties, contain developmentally appropriate screening content and language, require little or no staff training for implementation, potentially self-administered, with data entered using electronic platforms for inclusion into EHR, and be available in the public domain.

Proposed Screening Tool Requirements

The application must develop/adapt and test both a quick screen and a brief assessment tool for adoption at U.S. general medical or dental settings; and must meet the following requirements:

Budget and Funding Information

A total of $500,000 is anticipated to be provided for all projects selected through this notice in Fiscal Year 2012. Supplement requests must be less than $100,000 in direct costs, except for supplements of K awards: amount of the total funds requested on this cannot exceed the annual research funds allowed for the parent K award. In addition K award applications may not request additional salary support for the PI, but may request support for other program related expenses relating to (a) research expenses, such as supplies, equipment and technical personnel; and (b) statistical services including personnel and software/computer time up to the amount for research expenses allowed in the parent award.


The supplement request is for one year of funding. Applicants must hold an active grant funded by NIDA or NIDCR, under the following mechanisms: R00, R01, R34, R21, R23, R36, R37, K01, K02, K05, K08, K12, K20, K21, K23, K24, K25 and K99, U01, U18, U24, P01, P20, P30, P50 and P60) with a current project period end date of March, 2013 or later.  The parent grant must be active, and the research proposed in the supplement must be accomplished within 1 year.  Any necessary no cost extension should be in place before submission.   Before submitting a supplement application, potential applicants are highly encouraged to contact the program official of the parent grant to discuss the supplement plan and determine the responsiveness and pertinence of the potential application.

IMPORTANT:  The research proposed by the NIH grantee in the supplement application must be within the original scope of the NIH-supported grant project.  The funding mechanism being used to support this program, administrative supplements, can be used to cover cost increases that are associated with achieving certain new research objectives as long as they are within the original scope of the project.  Any cost increases need to result from making modifications to the project in order to take advantage of opportunities that would increase the value of the project consistent with its originally approved objectives and purposes.

Submitting an Administrative Supplement Request

To be considered for an administrative supplement, the request must be signed by the Authorized Organizational Representative/Signing Official (AOR/SO), and must describe the need for additional funding and the categorical costs.

Administrative supplement requests should be sent as attachments in an email, no later than 5pm (EST) on January 6, 2012, to:  

Applicants who prefer to submit hard copy (paper) requests should ensure that they are received no later than 5pm (EST) on January 6, 2012.  Requests to be addressed to:

NIDA Grants Management Branch
6001 Executive Boulevard
Room 4218, MSC 9560
Bethesda, MD 20892-9560, or for express delivery please use
Rockville, MD 20852

Requests should be submitted on the PHS398 Application Guide forms (font size and other formatting rules apply as designated in the instructions), as indicated below. Include only the following elements:

Cover Letter which cites this Notice, and the following information:

PHS 398 Form Page 1 (Face page)

PHS 398 Form Page 2

A brief proposal describing the project, including:


Administrative supplement requests will be reviewed administratively by NIH Staff. Selection factors will include the following:


Inquiries and discussion of plans for responding to this Notice are strongly encouraged.

NIDA Contact:

Geetha Subramaniam, M.D.
Medical Officer
National Institute on Drug Abuse
6001 Executive Boulevard
Room 3173, MSC 9593
Bethesda, Maryland 20892-9593
Telephone: 301-435-0974
FAX: 301-443-6814

NIDCR Contact:

David B. Clark, Dr.P.H.
National Institute of Dental and Craniofacial Research
6701 Democracy Blvd. Room 650
Bethesda, MD 20892-4878
Telephone:  301-594-4814

Weekly TOC for this Announcement
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