Notice of Intent to Publish a Program Announcement to Support
Research by Newly Independent Chemistry Investigators for the
Study of Drug Abuse and Addiction

Notice Number: NOT-DA-06-029

Key Dates
Release Date: September 19, 2006

Issued by
National Institute on Drug Abuse (NIDA), ( )

The National Institute on Drug Abuse (NIDA) plans to issue a Program Announcement (PAS) with set-aside funds, in the fall of 2006, designed to facilitate the entry of beginning investigators into basic chemistry research applied to drug abuse and addiction. NIDA recognizes the contributions that chemistry and related disciplines can make to understanding and treating drug abuse and addiction. In order to ensure the development and implementation of sustained, systematic applications of chemical expertise to drug abuse research, it is essential that opportunities for involvement in drug abuse research are made available to chemistry investigators who are at the early stages of establishing their independent research programs. Proposed principal investigators must be independent of a mentor at the time of award, but be at the beginning stages of his/her research career. To be appropriate for a CHEM/START award, research must be primarily focused on chemistry (e.g., synthetic, medicinal, computational, metabolic, natural products, targeted drug delivery, discovery of bioactive endogenous compounds). Thus, research on genetic, neural, or other biological processes would be appropriate for a CHEM/START award only if its overall emphasis were on understanding the chemical mechanisms involved. Development of chemical probes or related technologies to investigate specific outcomes or structure-activity relationships (SAR) also would be appropriate. Research proposed under CHEM/START need not be conducted in drug-abusing populations or involve administration of drugs; however, the relevance of the research to drug abuse or drug addiction must be clearly established in the application. All areas of chemical/metabolic sciences research related to drug abuse are sought under this announcement. Applications submitted in response to this PAS will be due at the regular NIH receipt dates, with the earliest being Feb 1, 2007.


For further information regarding this potential RFA, please contact: Rao Rapaka Chief, Chemistry and Physiological Systems Research Branch Division of Basic Neuroscience and Behavioral Research National Institute on Drug Abuse National Institutes of Health 6001 Executive Blvd., Rm. 4282, MSC 9555 Bethesda, Maryland 20892 Phone: 301-443-1887 Fax: 301-594-6043 E-mail:

Weekly TOC for this Announcement
NIH Funding Opportunities and Notices

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