NIDA ADMINISTRATIVE SUPPLEMENTS: TESTING MECHANISMS OF ACTION FOR
BEHAVIORAL THERAPIES FOR SUBSTANCE USE DISORDERS
RELEASE DATE: October 28, 2003
NOTICE: NOT-DA-04-002
National Institute on Drug Abuse (NIDA)
(http://www.nida.nih.gov)
APPLICATION RECEIPT DATE: January 23, 2004
PURPOSE
The National Institute on Drug Abuse (NIDA) announces the availability
of funds for administrative supplements to support the addition or
expansion of tests of mechanisms of action in NIDA-funded studies of
behavioral treatments for substance use disorders (SUDs). This
supplement program reflects NIDA’s ongoing commitment to the
comprehensive support of clinically-relevant behavioral treatment
research, as well as the recommendation of a scientific panel convened
in 2003 to help set priorities for such research at NIDA. This panel
agreed that major advances have been made in behavioral treatments for
drug abuse, and that the knowledge of the causal mechanisms of those
treatments could advance the field even further.
Supplements are intended to make maximum use of data being collected in
drug abuse treatment populations in order to understand better the
casual mechanisms of treatment. Supplements may be requested to include
(or expand on already-included) measures of therapy process or
potential mediators; to fund the audiotaping or videotaping of therapy
sessions or assessment activities; to rate or code therapy session or
assessment data; and/or to develop and test process measures or coding
systems targeting hypothesized therapeutic mechanisms of action. Strong
applications will test theory-based mechanisms of action, and will link
these mechanisms to clinically meaningful outcomes, including within-
session outcomes and overall treatment outcomes. Applications may
propose to test the mechanisms of action of a particular behavioral
treatment, or to test hypotheses about the common change mechanisms or
processes across several behavioral treatments. Applications may
address any treatment population, including adults, adolescents,
couples, families, and groups.
ELIGIBILITY
Supplements may be added to NIDA Research Project (R01) grants. Grants
eligible for supplementation must have at least 1 year remaining, and
the work proposed in the supplement must be completed by the end-date
of the parent grant. Supplemental projects must be within the general
scope of the parent grant. Questions about whether a project is within
the scope of the parent grant should be addressed to the designated
Program contact.
HOW TO APPLY
Supplement requests should be sent directly to NIDA’s Grants Management
Office (see address below). Requests should be in the form of a cover
page (using the PHS 398 form), a letter, and a budget justification,
each countersigned by the Principal Investigator of the parent grant
and the authorized business official at the PI’s institution. The
following sections should be included in the request letter, conforming
to a 5-page limit:
1. A brief description of the parent project on which the supplemental
project is based;
2. A discussion of the mechanism(s) of action to be studied in the
supplemental project;
3. A description of the proposed supplemental project, including
methodology, measures, statistical analyses, etc.;
4. A brief description of the qualifications of the research team.
Also, applicants should provide a budget justification that details the
budget items requested, including Facilities and Administrative costs.
The budget justification is not included in the 5-page limit of the
request letter.
REVIEW CRITERIA
Applications will be reviewed administratively, and it is expected
that, for those receiving awards, a resulting Supplemental Notice of
Grant Award will be issued within four months of the receipt deadline.
All funding decisions are final and are not subject to appeal.
Applications will be evaluated based on the strength of the rationale
for the hypothesized mechanisms under study, the ability of the
proposed supplemental project to test the mechanisms of interest, and
the expertise of the research team proposing to conduct the
supplemental study.
BUDGET INFORMATION
NIDA will commit $1.5 million in total costs to fund applications for
supplements submitted in response to this Notice. The maximum request
for direct costs is $75,000. Supplements are one-time awards and will
not be renewed. Any Facilities and Administrative (indirect) Costs also
should be specified in the budget request.
Awards pursuant to this Notice are contingent upon the availability of
funds and the receipt of a sufficient number of applications of high
scientific merit.
Receipt date: January 23, 2004
Earliest Award date: May 30, 2004
INQUIRIES
Direct inquiries regarding the program to:
Dr. Melissa W. Racioppo
Behavioral Treatment Development Branch
National Institute on Drug Abuse
6001 Executive Blvd. NSC Room 4230
Bethesda, MD 20892 (USPS)
Rockville, MD 20852 (FedEx and other couriers)
Tel: (301) 443-2261
Fax: (301) 443-6814
Email: mr313x@nih.gov
Direct inquiries regarding fiscal matters to:
Dr. Gary Fleming
Grants Management Branch
National Institute on Drug Abuse/NIH/DHHS
6101 Executive Boulevard
Suite 242, MSC 8403
Bethesda, MD 20892 (USPS)
Rockville, MD 20852 (express/courier service)
Tel: (301) 443-6710
Fax: 301-594-6849
Email: gf6s@nih.gov
Weekly TOC for this Announcement
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