Notice Number: NOT-CA-20-012
Release Date: February 21, 2020
First Available Due Date: March 18, 2020
Expiration Date: March 18, 2022
PA-18-591, Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
NATIONAL CANCER INSTITUTE (NCI)
The National Cancer Institute (NCI) SBIR Development Center recognizes that early-stage proof of concept studies can evolve rapidly, necessitating supplementary experiments and/or follow-on experiments for accelerated progress to position promising projects for stronger SBIR Phase II applications and to generate interest from follow-on investors and strategic partners. To accelerate the development of promising technologies, the NCI announces the opportunity for current NCI-funded SBIR Phase I grantees (R43 grant mechanism only) to seek supplemental project funding via the Administrative Supplement mechanism. The funds from these Administrative Supplements are intended to support research activities that are aimed at:
The funding can be used to cover additional costs that are associated with achieving new research objectives as long as they are within the original scope of the parent award. The supplement request must be for costs that result from adding a limited number of activities to advance the project to the next critical milestone(s) consistent with its originally approved aims and objectives. It is important to note that while the additional research and development funded by the supplement should advance the project forward, the scope is limited to the same product/technology, disease indication and overall goals as the parent award.
The technical objectives must represent activities that would advance the project to the next critical milestone in technology development. Specific activities to be proposed will vary depending on technical areas and stage of product development. Examples of activities that may be proposed include (but are not limited to):
Activities that are not supported include:
Application and Submission Information
Applications in response to this NOSI must be submitted using the following funding opportunity or its reissued equivalent:
All instructions in the SF424 (R&R) Application Guide and PA-18-591 must be followed, with the following additions:
Budget: Grantees with currently active NCI Phase I SBIR awards may propose Administrative Supplement budgets up to $150K direct costs.
Project Period: At the time of the supplement application, the grantees should have completed a substantial portion of the work proposed in the existing parent award and should have at least 3 months remaining in their parent award. The award must not be in no-cost extension at the time of application. The project period requested for all Administrative Supplements should be adequate to complete the proposed supplemental work but should not exceed one year from the proposed start date of the supplement.
Note: You are strongly encouraged to discuss your Administrative Supplement request in advance with the NCI SBIR Program Director listed on your NCI Phase I grant Notice of Award. The purpose is to receive pre-submission feedback on the proposed supplement work scope and its fit with this program.
Administrative Evaluation Criteria
NCI SBIR Program staff will consider whether the budget and the requested period of support are fully justified and reasonable in relation to the proposed research. Additionally, Program staff will evaluate applications using the following selection factors:
Please contact your NCI SBIR Program Director with any questions you may have regarding the NCI SBIR Administrative Supplement application requirements and process.
For all other questions, please contact:
Ashim Subedee, Ph.D.
National Cancer Institute (NCI)
Financial/Grants Management Contact
National Cancer Institute (NCI)