Notice of Intent to Publish the Reissuance of RFA-CA-18-026, "Improving the Reach and Quality of Cancer Care in Rural Populations (R01 Clinical Trial Required)"

Notice Number: NOT-CA-19-063

Key Dates

Release Date: July 26, 2019
Estimated Publication Date of Funding Opportunity Announcement: September 27, 2019
First Estimated Application Due Date: January 15, 2020
Earliest Estimated Award Date: October 01, 2020
Earliest Estimated Start Date :November 30, 2020

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The National Cancer Institute (NCI) intends to publish a Funding Opportunity Announcement (FOA) as a Request for Application (RFA) to solicit applications for Improving the reach and quality of cancer care in rural populations. This FOA is intended to be a reissuance of RFA-CA-18-026, "Improving the Reach and Quality of Cancer Care in Rural Populations (R01 Clinical Trial Required)".

This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.

The FOA is expected to be published in the Fall of 2019 with an expected application due date in early Winter 2020.

This FOA will utilize the R01 activity code. Details of the planned FOA are provided below.

Research Initiative Details

The purpose of this FOA is to reduce the burden of cancer and improve the quality of cancer care in rural areas among low-income and/or underserved populations. The FOA encourages two types of applications: 1) observational research that includes pilot testing of interventions to understand and address predictors of cancer care/treatment and outcomes in rural low-income and/or underserved populations; or 2) intervention research to address known predictors of cancer care/treatment and outcomes in rural low-income and/or underserved populations. Specifically, the focus for observational studies (with pilot testing) is understanding and addressing the predictive and/or mediating role of social determinants of health, barriers to care, and treatment; and the focus for interventional research is on addressing quality of care related to cancer diagnosis, treatment and/or survivorship. Most existing cancer control interventions are not ready for direct implementation and dissemination in low-income rural areas, so proposals should seek to develop, adapt, and/or implement, and test interventions.

This FOA will not focus on issues related to recruitment and retention of participants to clinical trials or other research studies; therefore, these would be considered non-responsive to the goals of this FOA and will not be reviewed.

This FOA will require that applicants define the rural population for the proposed study based on the non-metropolitan 2013 Rural-Urban Continuum Codes (RUCC) as defined at this link: Rural-Urban Continuum Codes.

Funding Information

Estimated Total Funding Up to $3.0 million in fiscal year 2021
Expected Number of Awards 4 - 6
Estimated Award Ceiling $500,000 or less in direct costs per year.
Primary CFDA Numbers 93.939

Anticipated Eligible Organizations

Public/State Controlled Institution of Higher Education
Private Institution of Higher Education
Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education)
Small Business
For-Profit Organization (Other than Small Business)
State Government
Indian/Native American Tribal Government (Federally Recognized)
County governments
Independent school districts
Public housing authorities/Indian housing authorities
U.S. Territory or Possession
Regional Organization
Applications are not being solicited at this time. 



Please direct all inquiries to:

Shobha Srinivasan, Ph.D.
National Cancer Institute (NCI)