Notice of Intent to Publish a Funding Opportunity Announcement for U.S. and Low- and Middle-Income Country (LMIC) HIV Malignancy Research Networks (U54)

Notice Number: NOT-CA-19-054

Key Dates

Release Date: June 18, 2019
Estimated Publication Date of Funding Opportunity Announcement: September 01, 2019
First Estimated Application Due Date: January 10, 2020
Earliest Estimated Award Date: July 01, 2020
Earliest Estimated Start Date: July 01, 2020

Related Announcements

Issued by
National Cancer Institute (NCI)


The National Cancer Institute intends to publish a Funding Opportunity Announcement (FOA) to solicit applications from eligible institutions of higher educations for specialized centers to conduct research in Low- and Middle-Income Countries (LMIC) with a significant burden of HIV-associated cancers.

This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.

The FOA is expected to be published in the Fall of 2019 with an expected application due date in early Winter 2020.

This FOA will utilize the U54 activity code. Details of the planned FOA are provided below.

Research Initiative Details

Each proposed network must develop a comprehensive research program that address questions in one topic by proposing up to three research projects, each focusing on relevant, complementary and synergistic areas of research in the proposed topic area that together will have an impact at the partnering LMIC and advance the field of science. Mechanistic clinical trial(s) will be allowed if they are hypothesis-driven studies that are trying to understand some component of the pathobiology of a cancer or a health-related outcome (no interventional trials). The research projects are to be developed and conducted as joint effort between the U.S. and LMIC investigators.

This FOA will be open to all investigators. These will be Multiple PD/PI applications, one PD/PI must be from a U.S. institution and one PD/PI from a LMIC institution. The Principal Investigators need to provide evidence that they have previously worked together. A network can be composed of institutions in one or more LMICs and one or more institutions in the U.S. Research projects can be led by early career investigators from the U.S. or LMIC. Each network can be supported by an Administrative Core, Developmental Core and needed shared resource cores.

Funding Information

Estimated Total Funding 6000000
Expected Number of Awards up to 6
Estimated Award Ceiling Application budgets will be limited to $800,000 in direct costs per year.
Primary CFDA Numbers TBD

Anticipated Eligible Organizations

Public/State Controlled Institution of Higher Education
Private Institution of Higher Education
Applications are not being solicited at this time. 


Please direct all inquiries to:

Geraldina Dominguez, Ph.D.
National Cancer Institute (NCI)