Notice of Intent to Publish a Funding Opportunity Announcement for Physical Sciences-Oncology Network (PS-ON): Physical Sciences-Oncology Projects (PS-OP) (U01 Clinical Trial Optional)

Notice Number: NOT-CA-19-005

Key Dates

Release Date:October 23, 2018
Estimated Publication Date of Funding Opportunity Announcement: November 30, 2018
First Estimated Application Due Date: January 30, 2019
Earliest Estimated Award Date: August 01, 2019
Earliest Estimated Start Date: September 01, 2019

Related Announcements

Issued by
National Cancer Institute (NCI)


The purpose of this Notice is to announce the NCI's intention to re-issue a Funding Opportunity Announcement (FOA) PAR-15-021 to invite U01 cooperative agreement applications for Physical Science-Oncology Projects (PS-OP). The goal of the Physical Sciences-Oncology Network (PS-ON) is to foster the convergence of physical sciences approaches and perspectives with cancer research to advance our understanding of cancer biology and oncology by forming transdisciplinary teams of physical scientists and cancer biologists/physician scientists. Examples of physical scientists may include engineers, physicists, mathematicians, chemists, and computer scientists. The PS-OPs, individually and as a collaborative Network along with other PS-OPs and the Physical Sciences-Oncology Centers (PS-OC), will support transdisciplinary research that: (1) establishes a physical sciences perspective within the cancer research community; (2) facilitates team science and field convergence at the intersection of physical sciences and cancer research; and (3) collectively tests physical sciences-based experimental and theoretical concepts of cancer and promotes innovative solutions to address outstanding questions in cancer research.

This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.

The FOA is expected to be published in November/December 2018 with expected application due date in January/February 2019.

The FOA will utilize the U01 (Research Project-Cooperative Agreements) activity code to support a discrete, specified, circumscribed project to be performed by a small team of investigators with combined expertise in the physical sciences (e.g., engineers, physicists, mathematicians, chemists, computer scientists) and cancer research (e.g., cancer biology, oncology, pathology).

Research Initiative Details

The aim of the PS-ON is to integrate physical sciences and cancer research perspectives and approaches to address complex and challenging questions in cancer research. This FOA re-issuance for PS-OPs will invite a broad range of research that addresses important cancer questions from a physical sciences perspective. Applicants may focus on one of the suggested thematic areas of the physical dynamics of cancer or spatio-temporal organization and information transfer in cancer. Other physical sciences-based thematic areas are also welcome, such as investigating the role of evolutionary theory in cancer or de-convoluting the complexity of cancer, or integrating multiple thematic areas into a discrete, specified, circumscribed collaborative research project. Refer to PAR-15-021 for details.

Funding Information

Estimated Total Funding TBD
Expected Number of Awards TBD
Estimated Award Ceiling TBD
Primary CFDA Numbers 93.393, 93.394, 93.395, 93.396, 93.399, 93.286

Anticipated Eligible Organizations

Public/State Controlled Institution of Higher Education
Private Institution of Higher Education
Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education)
Nonprofit without 501(c)(3) IRS Status (Other than Institution of Higher Education)
Small Business
For-Profit Organization (Other than Small Business)
State Government
Indian/Native American Tribal Government (Federally Recognized)
County governments
City or township governments
Special district governments
Independent school districts
Public housing authorities/Indian housing authorities
Indian/Native American Tribally Designated Organization (Native American tribal organizations (other than Federally recognized tribal governments)
U.S. Territory or Possession
Indian/Native American Tribal Government (Other than Federally Recognized)
Regional Organization

Applications are not being solicited at this time.


Please direct all inquiries to:

Nastaran Zahir, Ph.D.
National Cancer Institute (NCI)