Notice Number: NOT-CA-18-002
Release Date: November 2, 2017
Response Date: December 15, 2017
National Cancer Institute (NCI)
Through this Request for Information (RFI), the Office of Cancer Complementary and Alternative Medicine (OCCAM) of the National Cancer Institute is seeking information on:
This solicitation is being issued to provide information to assist in formulating potential programs to analyze the impact of lifestyle on the outcome of cancer therapy. Response to this RFI is voluntary. Responders are free to address any or all of the items in Sections I and II, delineated below, or any other relevant topics respondents recognize as important for NIH to consider. Respondents should not feel compelled to address all items.
Lifestyle and behavioral factors such as physical activities, exercises, diet, and stress reduction measures such as yoga and meditation, have been reported to affect human health and wellbeing. Some of these factors are also considered important for cancer prevention. However, there is a gap in our knowledge regarding the effects of these factors on the outcome of cancer therapies such as chemotherapy, radiation therapy, hormone therapy or immunotherapy. Specifically, NCI is interested in understanding how these factors in cancer patients affect the outcome of the treatment as measured by response to therapy, post treatment survival, relapse-free survival and quality of life during and after therapy. The responses to this RFI will be considered by OCCAM in developing future research programs to fill knowledge gaps by creating or identifying resources with relevant information. There is no solicitation available at this time; no basis for claims against NCI shall arise as a result of this RFI, responses thereto or the NCI’s use of such information as either part of our evaluation process or in developing specifications for any subsequent requirement.
NIH recognizes the complexity of this multifactorial topic. There are many different lifestyle and behavioral factors and the role of each one may vary by patient age, disease, disease stage, ethnicity, and therapy. Such factors must be considered when determining what, when, and how lifestyle and behavior affect the outcome of cancer therapy. The NIH seeks information on any or all of the following topics to help formulate strategic approaches to prioritizing its programmatic efforts.
SECTION I. Information on existing cancer informational resources that include lifestyle and behavioral information and outcomes of cancer therapies
SECTION II. Information on ongoing cancer therapy research projects or clinical trials where there is an opportunity to collect additional information on lifestyle and behavioral factors.
SECTION III. Information on potential planed or new research projects or clinical trials which can be designed specifically to study lifestyle and behavioral factors contributing to the effectiveness of cancer therapies
SECTION IV. Any other approaches not listed above aimed to:
Comments on the topic areas of interest should be submitted electronically to the following link: https://goo.gl/forms/avHjrMSXiwBTzLjo2 .
To ensure consideration, responses must be communicated by December 15, 2017.
We look forward to your input and hope that you will share this RFI document with your colleagues.
Please direct all inquiries to:
Avraham Rasooly, Ph.D.
National Cancer Institute (NCI)