Notice of Intent to Publish a Funding Opportunity Announcement for Core Infrastructure and Methodological Research for Cancer Epidemiology Cohorts (UM1)

Notice Number: NOT-CA-14-013

Key Dates
Release Date: December 18, 2013
Estimated Publication Date of Announcement:  Spring 2014 
First Estimated Application Due Date:  July 2014 
Earliest Estimated Award Date:  December 2014 
Earliest Estimated Start Date:  January 2015

Related Announcements


Issued by
National Cancer Institute (NCI)


The National Cancer Institute intends to reissue a Funding Opportunity Announcement (FOA) to solicit
applications for the support of the establishment, maintenance, or upgrade of Cancer Epidemiology Cohort (CEC; core functions, such as recruitment, retention, and biospecimen collection.  Methodological research to validate or evaluate new or existing approaches to core infrastructure functions (for example, validation of novel approaches to exposures assessment) is also appropriate.

This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. 

The FOA is expected to be published in the Spring 2014 with an expected application due date in the Summer 2014.

This FOA will utilize the UM1 (Research Project with Complex Structure Cooperative Agreement) activity code. Details of the planned FOA are provided below.

Research Initiative Details

The planned FOA will be open to:

1) Investigators/institutions maintaining Cancer Epidemiology Cohorts with at least 10,000 study participants that are capable of supporting studies to examine the effects of multiple exposures and study participants’ characteristics on the risk of multiple types of incident cancers and cancer mortality; and

2) Investigators/institutions maintaining cohorts of cancer patients, including high-risk family members for hereditary syndromes, of at least 5,000 participants (for smaller patient cohorts, NCI will considered responsiveness to this FOA on a case-by-case basis) for research addressing determinants of cancer incidence, prognosis, progression, and cancer/health-related outcomes.

Cohorts established to assess the role of exposures in the workplace on risk of cancer (i.e., “occupational cohorts”) may be appropriate for this FOA, but only if they were established to examine a broad range of exposures potentially experienced by the general public and/or genomic factors affecting cancer risk or outcomes after cancer diagnosis. Similarly, cancer surveillance activities and development and maintenance of registries of persons with particular characteristics that do not address identification of factors affecting cancer risk, outcomes, or cancer-related conditions are not appropriate for this FOA.



Please direct all inquiries to:

Daniela Seminara, Ph.D., M.P.H
National Cancer Institute (NCI)
Telephone: 240-276-6748