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NOT-CA-10-024: Administrative Supplements to Promote Research Collaborations in AIDS-Associated Malignancies for Projects Currently Funded by the National Cancer Institute (NCI) Administrative Supplements to Promote Research Collaborations in AIDS-Associated Malignancies for Projects Currently Funded by the National Cancer Institute (NCI)

Notice Number: NOT-CA-10-024

Key Dates
Release Date: May 19, 2010
Request Receipt Date: July 1, 2010
Earliest Anticipated Start Date for Supplement Awards: September 2010

Issued by
National Cancer Institute (NCI) (http://cancer.gov/)

Purpose

The National Cancer Institute (NCI) announces for Federal fiscal year 2010 the opportunity for grantees to seek supplemental funding for existing NCI-funded grants.  The purpose of this initiative is to stimulate collaborative research on AIDS-associated malignancies between NCI-funded investigators and AIDS researchers.  For the purposes of this initiative, the term “AIDS-associated malignancies” includes both AIDS-defining malignancies and other (i.e. non-AIDS defining) malignancies, whose incidence is increased in the setting of HIV infection.

BACKGROUND

Many of the most novel and exciting advances in AIDS-associated malignancies derive from the synthesis of previously disparate fields of research.  For such advances to be made, it is necessary for researchers with varying interests (possibly in differing fields) to initiate collaborative research interactions.

This initiative, known as the Activities to Promote Research Collaborations in AIDS-Associated Malignancies (APRC-AAM), can support novel collaborative activities in research that bring together new ideas and approaches from disparate scientific disciplines. The proposed supplement activities should be within the overall scope of the active parent NCI grant.

ELIGIBILITY REQUIREMENTS

  1. The requestor must be the principal investigator (PI) of an active R01, R37, P01, U01, R33, R42, or R44 “parent” grant. No other grant mechanisms are eligible for this program.
  2. The parent grant must have at least one full year remaining at the time of anticipated funding of Administrative Supplements (September 1, 2010). Requests for no-cost extensions on the parent grant to accommodate an APRC supplement will not be granted.
  3. Research proposed in the request must be accomplished within the project period of the parent grant.
  4. The proposed collaborative activity must remain within the overall scope of the active “parent” award but must also reflect new collaborative interactions that enhance the originally funded project.
  5. Collaborating investigators may come from the same or different departments within an institution, or from different institutions.

The funding mechanism being used to support this program, administrative supplements, can be used to cover cost increases that are associated with achieving certain new research objectives as long as they are within the original scope of the project. Any cost increases need to result from making modifications to the project in order to take advantage of opportunities that would increase the value of the project consistent with its originally approved objectives and purposes.

Although the financial plans of the NCI provide support for this program, administrative supplement awards pursuant to this initiative are contingent upon the availability of funds and the receipt of a sufficient number of meritorious requests.

A full description of the NCI APRC-AAM Program and the FY10 guidelines can be found at https://dcb.nci.nih.gov/News/Pages/FY10%20NCI%20ApplicationstoPromoteResearchCollaborationinAIDS-AssociatedMalignancies.aspx WILL BE ADDED SOON. On those web pages, the opportunities available to NCI grantees for collaborative activities funded with administrative supplements to their active grants and the mechanisms for requesting these supplements are described.

IMPORTANT:  The research proposed by the NIH grantee in the supplement application must be within the original scope of the NIH-supported grant project.  The funding mechanism being used to support this program, administrative supplements, can be used to cover cost increases that are associated with achieving certain new research objectives as long as they are within the original scope of the project.  Any cost increases need to result from making modifications to the project in order to take advantage of opportunities that would increase the value of the project consistent with its originally approved objectives and purposes.

PRE-SUBMISSION CONSULTATION

The program is anticipated to be highly competitive with limited funding. Therefore, before submitting a request , interested researchers are strongly encouraged to contact their NCI Program Directors to verify whether the “parent” grant and the anticipated new collaborations meet the eligibility criteria outlined above.

SUBMITTING A REQUEST

Requests for the NCI APRC-AAM administrative supplements must be prepared and submitted to the NCI as described in the NCI APRC-AAM Program Guidelines (http://dcb.nci.nih.gov/newsdetail.cfm?ID=36).

This Notice is a one-time announcement and formal requests must be received on or before July 1, 2010.Requests must be signed by the Authorized Organizational Representative (AOR) at the grantee institution.

NOTE: The NIH Center for Scientific Review IS NOT involved in receipt and processing of these requests. Supplement requests are not to be submitted electronically via Grants.gov or eRA, or in paper to the Division of Receipt and Referral, CSR.

Applicants are strongly encouraged to submit requests electronically as an e-mail attachment in PDF format; however, the signature of the AOR must be clearly visible. The e-mail address for electronic submission is: whitest@mail.nih.gov.

Applicants may also submit applications in paper format (original and 2 copies) to:

NCI Activities to Promote Research Collaborations in AIDS-Associated Malignancies

c/o Stephen White
NCI-APRC AAM Programs Manager
Division of Cancer Biology
National Cancer Institute, NIH, HHS
6130 Executive Boulevard, EPN Room 5048
Bethesda, MD 20892-7150 (U.S. Postal Service)
Rockville, MD 20852 (non-U.S.P.S. delivery)

Inquiries

Interested investigators may direct general inquiries regarding the NCI APRC-AAM to:

Betsy Read-Connole, Ph.D.
NCI APRC-AAM Program Director
Division of Cancer Biology
National Cancer Institute, NIH
EPN Room 5016, MSC 7398
6130 Executive Boulevard,
Bethesda, MD 20892-7398
Telephone: (301) 496-9740
E-mail: bconnole@mail.nih.gov

Direct all financial and grants management-related inquiries to:
Joy Kearse
Grants Management Specialist
Office of Grants Administration
National Cancer Institute, NIH
Telephone: 301-846-1010
kearsej@mail.nih


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