NOT-CA-03-022: AVAILABILITY OF NATIONAL SURGICAL ADJUVANT BREAST AND BOWEL PROJECT B-28 CLINICAL TRIAL TISSUE MICROARRAY

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and Human Services (HHS)

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AVAILABILITY OF NATIONAL SURGICAL ADJUVANT BREAST AND BOWEL PROJECT B-28
CLINICAL TRIAL TISSUE MICROARRAY

RELEASE DATE:  April 11, 2003 

NOTICE:  NOT-CA-03-022

National Cancer Institute (NCI)
 (http://www.nci.nih.gov)

The National Cancer Institute, and the National Surgical Adjuvant 
Breast and Bowel Project (NSABP), announce a one time only opportunity 
for investigators from US and non-US academic centers to evaluate 
candidate markers on breast cancer specimens from a large clinical 
trial. Strong preclinical and pilot clinical supportive data must be 
provided in the proposal.

The tissue microarray consists of specimens from 2,000 cases enrolled 
into the NSABP trial B-28. The B-28 trial assessed the worth of adding 
taxol to standard adriamycin cyclophosphamide regimen in the treatment 
of axillary node positive breast cancer. Therefore the tissue 
microarray set from B-28 is ideal for evaluating candidate predictive 
markers of taxol response/resistance. 

INQUIRIES:

For further information and to receive the announcement for this 
competition, send your name and e-mail address to:

Roger Aamodt, Ph.D.
Chief, Resources Development Branch
Cancer Diagnosis Program, NCI
EPN 6035A, 6130 Executive Boulevard
Rockville, MD 20892
Phone:  301 496-7147
FAX:  301 402-7819
E-mail:  [email protected]

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