Key Dates

Related Announcements

• February 15, 2024 - Notice of Special Interest (NOSI): Innovative Technologies for Research on Climate Change and Human Health. See Notice NOT-ES-24-002. 
• July 12, 2023 - PHS 2023-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed). See NOFO PA-23-230.
• July 12 2023 - PHS 2023-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required). See NOFO PA-23-231.
• July 12, 2023 - PHS 2023-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed).See NOFO PA-23-232.
• July 12 2023 - PHS 2023-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required). See NOFO PA-23-233.

Issued by

National Center for Complementary and Integrative Health (NCCIH)

Purpose

This Notice informs potential applicants that the National Center of Complementary and Integrative Health (NCCIH) is participating in NOT-ES-24-002: Notice of Special Interest (NOSI): Innovative Technologies for Research on Climate Change and Human Health effective as of November 20, 2024. 

The following text has been added to reflect the NCCIH's participation in this Notice of Special Interest (NOSI)::

Components of Participating Organizations

Issued by

National Center for Complementary and Integrative Health (NCCIH)

Purpose

NCCIH

The mission of the National Center for Complementary and Integrative Health (NCCIH) is to determine, through rigorous scientific investigation, the fundamental science, usefulness, and safety of complementary and integrative health approaches and their roles in improving health and health care (see NCCIH’s Strategic Plan). Examples of complementary and integrative health approaches include those with physical and/or psychological therapeutic inputs, often called mind and body interventions (e.g., yoga, tai chi, qi gong, meditation/mindfulness, hypnosis, music therapy, and art therapy), and approaches with dietary or nutritional therapeutic inputs (e.g., dietary supplements, plant-based products, and probiotics). Also of interest are multi-component interventions such as a combination of two or more complementary health approaches or integrated approaches to care in which a complementary health approach is used in combination with standard care. Applications will not be considered by NCCIH if they propose trials of regulated products (e.g., dietary supplements, devices, or biologics) for indications that have not been approved or cleared by the U.S. Food and Drug Administration. NCCIH will only support assignment of applications that include complementary and integrative health approaches.

Examples of approaches and technologies of interest to the NCCIH include, but are not limited to, the following examples:

• Tools that integrate ecological and climate data to study or address the effects of climate change on the maintenance of ecosystem services in biodiversity hotspots that are sources of novel natural products and traditional indigenous complementary and integrative health interventions.  
• Approaches and technologies to reduce stress and improve resilience and well-being in the face of climate-related stressors.
• Modeling and prediction tools, particularly those that leverage AI/ML approaches, for capturing the impacts of planetary health, resilience, and whole person health as they relate to climate change and health.
• Innovative tools and strategies to improve the dissemination and implementation of evidence-based complementary and integrative health approaches to reduce climate-related health risks and/or promote positive health processes in the face of climate-related stressors. 

Application and Submission Information

Applicants must select the IC and associated notice of funding opportunities (NOFOs) to use for submission of an application in response to this NOSI. The selection must align with the IC requirements listed above in order to be considered responsive to that NOFO. Non-responsive applications will be withdrawn from consideration for this initiative. In addition, applicants using NIH Parent Announcements (listed below) will be assigned to those ICs on this NOSI that have indicated those NOFOs are acceptable and based on usual application-IC assignment practices.

This NOSI applies to due dates on or after April 5, 2024, and subsequent receipt dates through April 5, 2025,

Submit applications for this initiative using one of the following notice of funding opportunities or any reissues of these announcements through the expiration date of this notice.

All instructions in the SF424 (R&R) Application Guide and the notice of funding opportunities used for submission must be followed, with the following additions:

• For funding consideration, applicants must include "NOT-ES-24-002" in the Agency Routing Identifier field (box 4B) of the SF424 R&R form. Applications without this information in box 4B will not be considered for this initiative. Applicants must select the IC and associated NOFO to use for submission of an application in response to the NOSI. The selection must align with the IC requirements listed in order to be considered responsive to that NOFO.

Applications nonresponsive to terms of this NOSI will not be considered for the NOSI initiative.

Inquiries

Please direct all inquiries to:

For general inquiries or studies related to natural product research, please contact:

Patrick C. Still, PhD
Program Director
Basic and Mechanistic Research Branch
National Center for Complementary and Integrative Health (NCCIH)
Telephone: 301-682-1895
Email: [email protected]

For general inquiries or studies related to mind-body research, please contact:

Jennifer N. Baumgartner, Ph.D.
Program Director
Clinical Research in Complementary and Integrative Health Branch
National Center for Complementary and Integrative Health (NCCIH)
Telephone: 301-402-4084
Email: [email protected]