NOT-AT-14-002: Notice of NCCAM Participation in PAR-13-375 Nutrigenetics and Nutrigenomics Approaches for Nutrition Research (R01)

Notice of NCCAM Participation in PAR-13-375 "Nutrigenetics and Nutrigenomics Approaches for Nutrition Research (R01)"

Notice Number: NOT-AT-14-002

Key Dates
Release Date: December 5, 2013

Related Announcements
PAR-13-375

Issued by
National Center for Complementary and Integrative Health (NCCIH formerly NCCAM)

Purpose

The purpose of this Notice is to inform potential applicants that the National Center for Complementary and Alternative Medicine (NCCAM) will participate in PAR-13-375 "Nutrigenetics and Nutrigenomics Approaches for Nutrition Research (R01)." NCCAM’s interests are restricted to the study of dietary supplements and botanicals, especially as they contribute to health maintenance. Examples of the application of nutrigenetics and nutrigenomics approaches to dietary supplement and botanical research of interest to NCCAM include but are not limited to:

Impact of genetic polymorphisms on botanical and dietary supplement absorption, transport and metabolism
Impact of botanical and dietary supplements on gene expression that affect absorption, transport and metabolism in target tissues
Mechanisms by which specific dietary supplements and probiotics modulate intestinal physiology (transporters), barrier function, inflammation, and/or microbiome composition
Mechanisms by which nutrient sensing in the gut is transduced to extra- intestinal organs and tissues
Studies that explore the interaction/competition between various dietary supplements and nutrients for their absorption, transport, metabolism and elimination
Studies that explore the interaction/competition between various dietary supplements, botanicals and drugs for their absorption, transport, metabolism and elimination
Impact of nutrient excess and deficiency in health maintenance
Impact of prebiotics and resistant starches on intestinal function and host metabolism, and
Impact of probiotics and secreted probiotic factors on intestinal function and host metabolism

The following sections of PAR-13-375 have been updated to reflect the participation of NCCAM in this FOA.

Part 1. Overview Information

Components of Participating Organizations
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Cancer Institute (NCI)
Office of Dietary Supplements (ODS)
National Center for Complementary and Alternative Medicine (NCCAM)

Catalog of Federal Domestic Assistance (CFDA) Number(s)
93.847; 93.393, 93.396, 93.399, 93.361, 93.213)

Part 2. Section VII. Agency Contacts

Scientific/Research Contact(s)
Carol Pontzer
National Center for Complementary and Alternative Medicine (NCCAM)
Telephone: (240) 422-0636
Email: pontzerc@mail.nih.gov

Financial/Grants Management Contact(s)
George Tucker, MBA
National Center for Complementary and Alternative Medicine (NCCAM)
Telephone: (301) 594-9102
Email: gt35v@nih.gov

All other aspects of the FOA remain unchanged.

Inquiries

Please direct all inquiries to:

Carol Pontzer
National Center for Complementary and Alternative Medicine (NCCAM)
Telephone: (240) 422-0636
Email: pontzerc@mail.nih.gov