Notice of Intent to Publish a Funding Opportunity Announcement for Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Centers (MDSRC) (P50 Clinical Trial Optional)
Notice Number:
NOT-AR-25-004

Key Dates

Release Date:
February 14, 2024
Estimated Publication Date of Notice of Funding Opportunity :
May 01, 2024
First Estimated Application Due Date:
July 03, 2024
Earliest Estimated Award Date:
May 30, 2025
Earliest Estimated Start Date:
June 02, 2025
Related Announcements

None

Issued by

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

National Heart, Lung, and Blood Institute (NHLBI)

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

National Institute of Neurological Disorders and Stroke (NINDS)

Purpose

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), and the National Institute of Neurological Disorders and Stroke (NINDS), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), and National Heart, Lung and Blood Institute (NHLBI), intend to publish a Notice of Funding Opportunity (NOFO) to solicit applications for Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Centers (MDSRCs). These Centers promote collaborative basic, translational, and clinical research and provide important resources that can be used by the national muscular dystrophy research communities. The Centers also provide outstanding environments for the training of new researchers capable of addressing high priority objectives in muscular dystrophy research. Center investigators are expected to participate in important community outreach efforts to increase awareness of their research activities among people with lived experience and the related advocacy communities and to incorporate community perspectives into the conduct of patient-centered research.

This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.

The NOFO is expected to be published in Spring 2024 with an expected application due date in Summer 2024.

Only New and Renewal applications will be eligible.

This NOFO will utilize the P50 activity code. Details of the planned NOFO are provided below.

Research Initiative Details

This Notice encourages investigators with expertise and insights into basic and clinical muscular dystrophy research to begin to consider applying for this NOFO.

In addition, collaborative investigations combining expertise in physiology, cardiology, pulmonology, neurology, bioinformatics, bioengineering or other relevant fields will be encouraged, and these investigators should also begin considering applying for this application.

Among the areas of research encouraged in this initiative are patient-oriented and synergistic pre-clinical research examining the mechanisms that underlie the effects of muscular dystrophies as well as research designed to improve the translation of existing knowledge of strategies for the prevention and treatment of muscular dystrophies.

Funding Information

Estimated Total Funding

The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.

NIH intends to commit a total of $4,800,000, for fiscal year 2025. Future year amounts will depend on annual appropriations.

Expected Number of Awards

The participating NIH institutes expect to fund a total of three Centers through this NOFO.

Estimated Award Ceiling


Applicants may request up to $1,000,000 direct costs/year (exclusive of facilities and administrative costs of subcontractors with collaborating organizations) for up to five years

Primary Assistance Listing Number(s)

TBD

Anticipated Eligible Organizations
Public/State Controlled Institution of Higher Education
Private Institution of Higher Education
Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education)
Small Business
For-Profit Organization (Other than Small Business)
State Government
Indian/Native American Tribal Government (Federally Recognized)
County governments
Independent school districts
Public housing authorities/Indian housing authorities
Indian/Native American Tribally Designated Organization (Native American tribal organizations (other than Federally recognized tribal governments)
U.S. Territory or Possession
Indian/Native American Tribal Government (Other than Federally Recognized)
Non-domestic (non-U.S.) Entity (Foreign Organization)
Regional Organization
Eligible Agencies of the Federal Government

Applications are not being solicited at this time. 

Inquiries

Please direct all inquiries to:

Emily F. Carifi, Ph.D.
National Institute of Arthritis and Musculoskeletal and Skin Diseases
Telephone: 301-496-0665
Email: [email protected]


Weekly TOC for this Announcement
NIH Funding Opportunities and Notices