CLINICAL CENTERS FOR THE OSTEOARTHRITIS INITIATIVE Release Date: July 19, 2001 NOTICE: NOT-AR-01-009 RFP AVAILABLE: NIH-NIAMS-02-03 National Institute of Arthritis and Musculoskeletal and Skin Diseases National Institute on Aging The National Institute of Arthritis and Musculoskeletal and Skin Diseases and the National Institute on Aging, National Institutes of Health, is seeking proposals for a multi-center, longitudinal, prospective, population-based study of knee osteoarthritis (OA) to develop a public domain research resource. The purpose of this resource is to facilitate the scientific evaluation of biomarkers for osteoarthritis (OA) as potential surrogate endpoints for disease onset and progression. This Request for Proposals is to solicit the individual Clinical Centers that will be enrolling subjects and collecting data. The objectives of each Clinical Center are to: 1) cooperate with the Data Coordinating Center in implementing the overall Osteoarthritis Initiative; and 2) recruit, enroll and follow for 4 years individuals from the general population, over the age of 50 at high risk for the development of osteoarthritis (i.e., obesity, previous knee injury, low grade knee pain, an abnormal gait, etc.) It is intended that minorities and women will be represented in proportions similar to those found in the U.S. population over the age of 50. Each Clinical Center will recruit 1000-1250 individuals for study. It is anticipated that four to six cost reimbursement contract awards will be made for a period of seven years beginning on or about July 15, 2002. The solicitation NIH-NIAMS-02-03 will be available electronically on or about fifteen days from the date of this notice and may be accessed through the Internet at the following address: http://www.nih.gov/niams/grants/rfp/rfplist.htm. Proposals will be due on or about November 7, 2001. Offerors are responsible for downloading their own copy of the solicitation and amendments and for routinely checking the Internet site for any possible solicitation amendments that may be issued by the Government. All responsible sources may submit proposals which will be considered by the Government. The North American Industrial Classification System (NAICS) code for this acquisition is 541710. This advertisement does not commit the Government to award a contract. Inquiries may be directed to: Eileen Webster-Cissel Chief Contracting Officer Contracts Management Branch, EP National Institute of Arthritis and Musculoskeletal and Skin Diseases Natcher Building, Room 5AS13A 45 Center Drive, MSC 6500 Bethesda, Maryland 20892-6500 Telephone: 301-594-2543 FAX: 301-480-4543 Email address: ew52c@nih.gov
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