Notice Number: NOT-AI-19-046
Release Date: February 28, 2019
Response Date: March 28, 2019
National Institute of Allergy and Infectious Diseases (NIAID)
National Cancer Institute (NCI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute on Minority Health and Health Disparities (NIMHD)
This notice is a time-sensitive Request for Information (RFI) inviting comments and suggestions on the framework for a Trans-NIH Strategic Plan to Cure Hepatitis B.
NOTE: It is important to read this entire RFI notice to ensure an adequate response is prepared and to have a full understanding of how your response will be utilized.
NIH is developing a strategic plan to cure hepatitis B. The strategic plan aligns with NIH's ongoing efforts to intensify innovative hepatitis B research, and with the HHS-wide National Viral Hepatitis Action Plan.
The trans-NIH strategic plan will be structured around three areas of research vital to developing a cure for hepatitis B. A cure is defined as a sustained loss of hepatitis B surface (HBs) antigen, with or without the presence of antibodies against HBs, and undetectable hepatitis B virus (HBV) DNA in serum after completion of a finite course of treatment.
Strategic Priority 1: Understand Hepatitis B Biology
Strategic Priority 2: Develop Tools and Resources
Strategic Priority 3: Develop Strategies to Cure Hepatitis B
This RFI seeks input from stakeholders throughout the scientific research community and the general public regarding the above proposed framework.
NIH seeks comments on any or all of, but not limited to, the following topics in hepatitis B cure research:
How to Submit a Response
All comments must be submitted electronically on the submission website.
Responses (no longer than 500 words in MS Word or pdf format) must be received by 11:59:59 pm (ET) on March 29, 2019 . You will see an electronic confirmation acknowledging receipt of your response
Responses to this RFI are voluntary. Do not include any proprietary, classified, confidential, trade secret, or sensitive information in your response. The responses will be reviewed by NIH staff, and individual feedback will not be provided to any responder. The Government will use the information submitted in response to this RFI at its discretion. The Government reserves the right to use any submitted information on public NIH websites, in reports, in summaries of the state of the science, in any possible resultant solicitation(s), grant(s), or cooperative agreement(s), or in the development of future funding opportunity announcements.
This RFI is for information and planning purposes only and shall not be construed as a solicitation, grant, or cooperative agreement, or as an obligation on the part of the Federal Government, the NIH, or individual NIH Institutes and Centers to provide support for any ideas identified in response to it. The Government will not pay for the preparation of any information submitted or for the Government’s use of such information. No basis for claims against the U.S. Government shall arise as a result of a response to this request for information or from the Government’s use of such information.
We look forward to your input and hope that you will share this RFI document with your colleagues.
Please direct all inquiries to: