Notice of Correction to Instructions for Application Submission for PAR-17-237 "Centers for AIDS Research (P30)"

Notice Number: NOT-AI-17-024

Key Dates
Release Date: April 24, 2017

Related Announcements
PAR-17-237

Issued by
National Institute of Allergy and Infectious Diseases (NIAID)

Purpose

The purpose of this notice is to correct the application submission instructions for the Developmental Core Budget, the Clinical Science Core Research Strategy, and Additional Core Research Strategy in PAR-17-237, "Centers for AIDS Research (P30)."

Section IV. Application and Submission Information

2. Content and Form of Application Submission

Developmental Core

Budget (Developmental Core)

Current language:

Budget forms appropriate for the specific component will be included in the application package.

The Developmental Core budget may include equipment, supplies, support contracts, and other necessary expenses.  All items should be fully justified for allocation of CFAR funds within the Budget Justification.  Any budget requested for support of the Developmental Core Director must match the effort associated with the Developmental Core work conducted by the Developmental Core Director.  Applicants may request support for early career investigator salary for scientific developmental projects with justification.

Applicants may include travel funds to support early career faculty to attend a scientific meeting to present the results from their CFAR Developmental Project award.   CFAR funds cannot be used to provide travel scholarships for investigators with a CFAR developmental award.

Applicants should budget funds to support developmental projects that stimulate interest in HIV/AIDS research. These funds may be used by early career investigators in the HIV/AIDS field with novel, high risk project ideas and investigators not in the HIV/AIDS research field to encourage them to explore novel approaches to HIV/AIDS research questions.  Applicants may use these funds to support mentoring of early career investigators in order to achieve success in applying for external research funding.    Senior investigators in HIV/AIDS research field are not eligible for developmental project awards except in rare circumstances and must have prior approval from NIH Program Staff.

In the budget justification section, applicants may include any in-kind support the Core receives such as operating budgets provided by the institution, large gifts, dedicated space, direct support of infrastructure core personnel, and dedicated equipment, including support for research infrastructure-related functions such as directing or managing the Core, and similar activities. This information may be presented in tabular form.

Note: The R&R Budget form included in many of the component types allows for up to 100 Senior/Key Persons in section A and 100 Equipment Items in section C prior to using attachments for additional entries. All other SF424 (R&R) instructions apply.

Revised language:

Budget forms appropriate for the specific component will be included in the application package.

The Developmental Core budget may include equipment, supplies, support contracts, and other necessary expenses.  All items should be fully justified for allocation of CFAR funds within the Budget Justification.  Any budget requested for support of the Developmental Core Director must match the effort associated with the Developmental Core work conducted by the Developmental Core Director.  Applicants may request support for early career investigator salary for scientific developmental projects with justification.

Applicants may include travel funds to support early career faculty to attend a scientific meeting to present the results from their CFAR Developmental Project award.   CFAR funds cannot be used to provide travel scholarships for investigators without a CFAR developmental award.

Applicants should budget funds to support developmental projects that stimulate interest in HIV/AIDS research. These funds may be used by early career investigators in the HIV/AIDS field with novel, high risk project ideas and investigators not in the HIV/AIDS research field to encourage them to explore novel approaches to HIV/AIDS research questions.  Applicants may use these funds to support mentoring of early career investigators in order to achieve success in applying for external research funding.    Senior investigators in HIV/AIDS research field are not eligible for developmental project awards except in rare circumstances and must have prior approval from NIH Program Staff.

In the budget justification section, applicants may include any in-kind support the Core receives such as operating budgets provided by the institution, large gifts, dedicated space, direct support of infrastructure core personnel, and dedicated equipment, including support for research infrastructure-related functions such as directing or managing the Core, and similar activities. This information may be presented in tabular form.

Note: The R&R Budget form included in many of the component types allows for up to 100 Senior/Key Persons in section A and 100 Equipment Items in section C prior to using attachments for additional entries. All other SF424 (R&R) instructions apply

Clinical Science Core

PHS 398 Research Plan (Clinical Science Core)

Current language:

Research Strategy:   Describe the role of the Clinical Science Core within the CFAR as a whole, and how the responsibilities of the Core will advance the mission and purpose of the CFAR.   Explain the general methods and approaches proposed to accomplish the specific aims, and the rationale for their selection.

  • Describe the overall purpose of the Clinical Science Core, and provide a management plan. This should include, for example, day-to-day operations such as scientific communication, training, and safety.
  • Describe the extent to which the Clinical Science Core provides added value to NIH-funded HIV/AIDS research conducted at the institution(s), including providing economies of scale.
  • Demonstrate the Core’s ability to support the research base which can include NIH funded projects that may be supported by the Core. 
  • Describe institutional support for the Clinical Science Core including allocation of space, salary support, equipment, and etc.
  • Indicate how early career investigators in the HIV/AIDS research area or faculty new to the HIV/AIDS research area will benefit from the Core services, including guidance or training in the development of protocols and regulatory documents for clinical research projects.  Describe how the Clinical Science Core will provide assistance to early career investigators.
  • Cite NIH-specific programs supported by the Core, and be specific about how each Core will provide support.
  • Describe the plans of the Clinical Science Core to foster synergy with other CFAR Cores and SWGs, and enhance HIV/AIDS research collaborations.
  • Describe the process used by the Clinical Science Core for prioritizing workload and Core usage with respect to evolving scientific priorities at the applicant institution.
  • Describe the Policies and Procedures for the proposed Clinical Science Core, including for example, how decisions are made, frequency of internal progress reporting, the strategic planning processes, and process for reallocating funds within the Core as needed.
  • Describe procedures for obtaining assessments from HIV/AIDS investigators about the Core’s ability to meet research needs.
  • Describe detailed plans for a recharge system, wherein costs associated with this Core are recovered using a proposed fee to the end user, and demonstrate how recovered costs will be allocated to additional CFAR activities, if applicable.
  • Describe how the Core will measure progress and evaluate outcomes.
  • Describe how cores with partial CFAR funding (e.g., leveraging existing Cores funded by NIH) will be used to enhance the research of CFAR investigators.
  • Describe how the Clinical Science Core will monitor and ensure Core User compliance with Human Subjects Protections in the processing of human tissues, samples or other research data obtained through multiple sources, including ongoing funded trials, research or CFAR repositories.

Revised language:

Research Strategy:   Describe the role of the Clinical Science Core within the CFAR as a whole, and how the responsibilities of the Core will advance the mission and purpose of the CFAR.   Explain the general methods and approaches proposed to accomplish the specific aims, and the rationale for their selection.

  • Describe the overall purpose of the Clinical Science Core, and provide a management plan. This should include, for example, day-to-day operations such as scientific communication, training, and safety.
  • Describe the extent to which the Clinical Science Core provides added value to NIH-funded HIV/AIDS research conducted at the institution(s), including providing economies of scale.
  • Demonstrate the Core’s ability to support the research base which can include NIH funded projects that may be supported by the Core. 
  • Indicate how early career investigators in the HIV/AIDS research area or faculty new to the HIV/AIDS research area will benefit from the Core services, including guidance or training in the development of protocols and regulatory documents for clinical research projects.  Describe how the Clinical Science Core will provide assistance to early career investigators.
  • Cite NIH-specific programs supported by the Core, and be specific about how each Core will provide support.
  • Describe the plans of the Clinical Science Core to foster synergy with other CFAR Cores and SWGs, and enhance HIV/AIDS research collaborations.
  • Describe the process used by the Clinical Science Core for prioritizing workload and Core usage with respect to evolving scientific priorities at the applicant institution.
  • Describe the Policies and Procedures for the proposed Clinical Science Core, including for example, how decisions are made, frequency of internal progress reporting, the strategic planning processes, and process for reallocating funds within the Core as needed.
  • Describe procedures for obtaining assessments from HIV/AIDS investigators about the Core’s ability to meet research needs.
  • Describe detailed plans for a recharge system, wherein costs associated with this Core are recovered using a proposed fee to the end user, and demonstrate how recovered costs will be allocated to additional CFAR activities, if applicable.
  • Describe how the Core will measure progress and evaluate outcomes.
  • Describe how cores with partial CFAR funding (e.g., leveraging existing Cores funded by NIH) will be used to enhance the research of CFAR investigators.
  • Describe how the Clinical Science Core will monitor and ensure Core User compliance with Human Subjects Protections in the processing of human tissues, samples or other research data obtained through multiple sources, including ongoing funded trials, research or CFAR repositories.

Additional Core

PHS 398 Research Plan (Additional Core)

Current language:

Research Strategy:   Describe the role of the Core within the CFAR as a whole, and how responsibilities of this Core advance the mission and purpose of the CFAR.  Explain the general methods and approaches proposed to accomplish the specific aims, and the rationale for their selection.

  • Describe the overall purpose of the Core, and provide a management plan.  This should include for example, day-to-day operations such as scientific communication, training, and safety.
  • Describe the extent to which the Core provides added value to NIH-funded HIV/AIDS research conducted at the institution(s), including providing economies of scale.
  • Demonstrate the Core’s ability to support the research base which can include NIH funded projects that may be supported by the Core. 
  • Describe institutional support for the Core including allocation of space, salary support, equipment, etc.
  • Indicate how early career investigators in the HIV/AIDS research area or faculty new to the HIV/AIDS research area will benefit from the Core services.  
  • Cite NIH-specific programs supported by the Core, and be specific about how each Core will provide support.
  • Describe the plans of the Core to foster synergy with other CFAR Cores and SWGs, and enhance HIV/AIDS research collaborations.
  • Describe the process used by the Core for prioritizing workload and Core usage with respect to evolving scientific priorities at the applicant institution.
  • Describe the Policies and Procedures for the proposed Core, including for example, how decisions are made, frequency of internal progress reporting, the strategic planning process, and the process for reallocating funds within the Core as needed.
  • Describe procedures for obtaining assessments from HIV/AIDS investigators about the Core’s ability to meet research needs.
  • Describe detailed plans for a recharge system, wherein costs associated with this Core are recovered using a proposed fee to the end user, and demonstrate how recovered costs will be allocated to additional CFAR activities if applicable.
  • Describe how the Core will measure progress and evaluate outcomes.
  • Describe how cores with partial CFAR funding (e.g., leveraging existing Cores funded by NIH) will be used to enhance the research of CFAR investigators.
  • Describe how the Additional Core will monitor and ensure Core User compliance with Human Subjects Protections and/or Animal Welfare Assurance in the processing of human or animal tissues, samples or other research data obtained through multiple sources, including ongoing funded trials, research or CFAR repositories.

Revised language:

Research Strategy:   Describe the role of the Core within the CFAR as a whole, and how responsibilities of this Core advance the mission and purpose of the CFAR.  Explain the general methods and approaches proposed to accomplish the specific aims, and the rationale for their selection.

  • Describe the overall purpose of the Core, and provide a management plan.  This should include for example, day-to-day operations such as scientific communication, training, and safety.
  • Describe the extent to which the Core provides added value to NIH-funded HIV/AIDS research conducted at the institution(s), including providing economies of scale.
  • Demonstrate the Core’s ability to support the research base which can include NIH funded projects that may be supported by the Core. 
  • Indicate how early career investigators in the HIV/AIDS research area or faculty new to the HIV/AIDS research area will benefit from the Core services.  
  • Cite NIH-specific programs supported by the Core, and be specific about how each Core will provide support.
  • Describe the plans of the Core to foster synergy with other CFAR Cores and SWGs, and enhance HIV/AIDS research collaborations.
  • Describe the process used by the Core for prioritizing workload and Core usage with respect to evolving scientific priorities at the applicant institution.
  • Describe the Policies and Procedures for the proposed Core, including for example, how decisions are made, frequency of internal progress reporting, the strategic planning process, and the process for reallocating funds within the Core as needed.
  • Describe procedures for obtaining assessments from HIV/AIDS investigators about the Core’s ability to meet research needs.
  • Describe detailed plans for a recharge system, wherein costs associated with this Core are recovered using a proposed fee to the end user, and demonstrate how recovered costs will be allocated to additional CFAR activities if applicable.
  • Describe how the Core will measure progress and evaluate outcomes.
  • Describe how cores with partial CFAR funding (e.g., leveraging existing Cores funded by NIH) will be used to enhance the research of CFAR investigators.
  • Describe how the Additional Core will monitor and ensure Core User compliance with Human Subjects Protections and/or Animal Welfare Assurance in the processing of human or animal tissues, samples or other research data obtained through multiple sources, including ongoing funded trials, research or CFAR repositories.

All other aspects of the FOA remain unchanged.

Inquiries

Please direct all inquiries to:

Ann Namkung Lee, M.P.H.
National Institute of Allergy and Infectious Diseases (NIAID)
Telephone: 240-627-3099
Email: an107z@nih.gov