RFP Announcement:  Nonhuman Primate Core Functional Genomics Laboratory for AIDS Vaccine Research and Development RFP NIAID-DAIDS-NIH-AI-2012-142

Notice Number: NOT-AI-12-031

Key Dates

Release Date:  May 18, 2012

Issued by

National Institute of Allergy and Infectious Diseases (NIAID)


The NIAID provides immunological and virological support for nonhuman primate (NHP) conducted at NIAID’s Simian Vaccine Evaluation Unit (SVEU) contract sites and by DAIDS-supported vaccine researchers through three existing NHP Core Laboratories (NHP Core Labs): the Humoral Immunology Core Lab, the Cellular Immunology Core Lab, and the Viral Ribonucleic Acid (RNA) Core Lab. The Functional Genomics NHP Core Laboratory will thus become a fourth NHP Core Lab. The objective of the Core Laboratories has been to insure standardization and comparability of functional genomics services and assays conducted for these SVEU and DAIDS-supported preclinical NHP studies.

The purpose of the proposed contract will be to provide support for a Functional Genomics NHP Core Laboratory for the conduct and improvement of assays designed to generate specific quantitative genomic expression profiles and network diagrams from RNA samples obtained from NHPs enrolled in priority SVEU protocols and DAIDS-supported investigator-initiated NHP studies.

The Contractor shall compile and analyze the generated data using bioinformatics and biocomputing tools (e.g., unbiased hierarchical clustering methods, sophisticated network algorithms, etc.) with the intent of identifying gene signatures that could potentially define correlates of protection and predict vaccine efficacy.

It is anticipated that one cost reimbursement, term type contract will be awarded for a 1-year Base period plus four 1-year options for a possible total period of performance of 5 years beginning on or about June 17, 2013. The performance requirement will be for the delivery of 3.85 full time equivalents (FTEs) per year for the base period (Year 1) and option periods (Years 2 through 5), which may be unilaterally exercised by the Government.  In addition, the Government may unilaterally exercise options to accommodate significant increases in work to be provided for the base period and option periods.  Should the Government elect to exercise these options, the Contractor shall provide resources for the unanticipated increase in work volume by .95 FTE for each option exercised.  The Government may exercise an option up to two times in any year of the contract. 

The NAICS Code is 541712 with a size standard of 500 employees.

Any responsible offeror may submit a proposal which will be considered by the Agency.  This RFP is available electronically as of May 14, 2012, and may be accessed through FedBizOpps http://www.fedbizopps.gov/.  This notice does not commit the Government to award a contract.  No collect calls will be accepted.  No facsimile transmissions will be accepted.


Please direct all inquiries to:

Robert Corno, Contract Specialist
Office of Acquisitions, Division of Extramural Activities, NIAID, NIH, DHHS
6700B Rockledge Drive Room 3214, MSC 7612 (Express mail:  Use Zip Code 20817)
Phone: 301-496-0612
Fax: 301-480-4675

John R. Manouelian, Contracting Officer
Office of Acquisitions, Division of Extramural Activities, NIAID, NIH, DHHS
6700B Rockledge Drive Room 3214, MSC 7612 (Express mail:  Use Zip Code 20817)
Phone: 301-496-0612
Fax: 301-480-4675

Weekly TOC for this Announcement
NIH Funding Opportunities and Notices

Office of Extramural Research (OER) - Home Page Office of Extramural
Research (OER)
  National Institutes of Health (NIH) - Home Page National Institutes of Health (NIH)
9000 Rockville Pike
Bethesda, Maryland 20892
  Department of Health and Human Services (HHS) - Home Page Department of Health
and Human Services (HHS)
  USA.gov - Government Made Easy
NIH . . . Turning Discovery Into Health

Note: For help accessing PDF, RTF, MS Word, Excel, PowerPoint, Audio or Video files, see Help Downloading Files.