Amendment to PAR-11-044 Indo-US Collaborative Program on Low-Cost Medical Devices (R03)

Notice Number: NOT-AI-11-020

Release Date: December 23, 2010

National Institute of Allergy and Infectious Diseases (NIAID)

The purpose of this Notice is to announce the participation of National Institute of Allergy and Infectious Diseases (NIAID) in the PAR-11-044 "Indo-US Collaborative Program on Low-Cost Medical Devices (R03)" http://grants.nih.gov/grants/guide/pa-files/PAR-11-044.html, provide some areas of interest to NIAID and to provide an NIAID contact.

NIAID is interested in research applications that address chronic respiratory disease, primary immunodeficiencies, HIV and tuberculosis.

Under Background and Scope the following topics should be added:

• Diagnostic and Other Infectious Diseases devices suitable for use in low resource settings.
  • Semi-quantitative HIV viral load
  • Tuberculosis diagnostics applicable to HIV positive or negative patients with the following applications:
    • Distinguish latent, reactivation, or primary tuberculosis infection.
    • Devices appropriate for use in BCG vaccinated populations.
    • Distinguish IRIS from recrudescence of tuberculosis during TB treatment.
    • Improved detection of hepatic or renal toxicity due to TB treatment.
    • Detection of TB in children, detection of paucibacillary TB, detection of extrapulmonary TB.
    • Technologies for monitoring treatment compliance (i.e. non-invasive samples suitable for determining drug levels).
    • Development of hand held ultrasound devices suitable for detection of abscesses of lymph node enlargement.
• hronic Respiratory Diseases monitoring and development.

Also under Background and Scope the bullet:

There is a need to screen newborns for treatable conditions with high morbidity and mortality such as hemoglobinopathies, hypothyroidism, and other metabolic or inherited disorders

Should now read:

There is a need to screen newborns for treatable conditions with high morbidity and mortality such as hemoglobinopathies, primary immunodeficiencies, hypothyroidism, and other metabolic or inherited disorders.

Components of Participating Organizations
National Institute of Biomedical Imaging and Bioengineering (NIBIB) (http://www.nibib.nih.gov)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)(http://www.nichd.nih.gov)

All other aspects of this Funding Opportunity Announcement remain unchanged.

Please direct all NIAID related inquiries to:

Karl Salzwedel, PhD
NIAID/DAIDS/BSP/PBRB
6700B Rockledge Rm 4149
Tel: 301-496-5332
Email:  [email protected]