NOT-AI-03-033: RFP ANNOUNCEMENT: PRODUCTION AND TESTING OF ANTHRAX RECOMBINANT PROTECTIVE ANTIGEN (rPA) VACCINE

Department of Health
and Human Services (HHS)
NIH... Turning Discovery Into Health^®

RFP ANNOUNCEMENT: PRODUCTION AND TESTING OF ANTHRAX RECOMBINANT PROTECTIVE 
ANTIGEN (rPA) VACCINE - RFP-NIH-NIAID-DMID-03-29

RELEASE DATE:  May 5, 2003

NOTICE: NOT-AI-03-033

National Institute of Allergy and Infectious Diseases (NIAID)
 (http://www.niaid.nih.gov)

RECEIPT DATE: June 30, 2003

DESCRIPTION

The Division of Microbiology and Infectious Diseases of the National 
Institute of Allergy and Infectious Diseases (NIAID) has a requirement 
to continue advanced development and production of a vaccine to protect 
the general United States population against inhalation anthrax when 
administered in an immunization series of not more than three doses. 
This RFP is intended to target vaccine candidate(s) that can be 
produced at a scale to support commercial manufacturing, have 
demonstrated protective efficacy of the vaccine in animal models, and 
have already been compared and evaluated clinically with the licensed 
anthrax vaccine in healthy adults of both genders. Studies leading to 
licensure are expected to: evaluate safety, develop the optimal dose 
and dose regimen and extend the age range and populations for which the 
vaccine will be indicated. Studies proposed in response to this RFP 
will be those required for a licensure path and consistent with 
intermediate-scale manufacturing and contract timelines. The Government 
contemplates awarding one or more contract(s) for accomplishing the 
tasks outlined in the Work Statement. It is anticipated that these 
contracts will have two to three year performance periods. RFP-NIH-
NIAID-DMID-03-29 will be available electronically on or about May 15 , 
2003, and may be accessed through the NIAID Contract Management Branch 
(CMB) Home Page by using the following electronic address and 
instructions: NIAID/CMB Home Page (via the WWW): Use 
http://www.niaid.nih.gov/contract to access the NIAID/CMB Home Page. 
Once at the NIAID/CMB Home Page, click on the RFPs link and then click 
on RFP NIH-NIAID-DMID-03-29. 

Responses to this RFP will be due on June 30, 2003. Any responsible 
offeror may submit a proposal for consideration by the Government. This 
advertisement does not commit the Government to award a contract. No 
collect calls will be accepted.

POINT OF CONTACT

Elizabeth J. Osinski Contracting Officer DHHS, NIH, NIAID, DEA, CMB 
6700- B Rockledge Drive, Rm # 2231 Bethesda, MD 20892-7612 (FedEx - 
20817-7612) e-mail: [email protected]; 301-402-0972 (Fax); 301-402-6289 (Phone).
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