BIODEFENSE AND EMERGING INFECTIOUS DISEASES RESEARCH OPPORTUNITIES Release Date: May 17, 2002 (see replacement PA-03-080) NOTICE: NOT-AI-02-023 National Institute of Allergy and Infectious Diseases (NIAID) (http://www.niaid.nih.gov) PURPOSES OF THIS NOTICE To inform the research community of the many research needs and opportunities in biodefense and emerging infectious diseases To encourage the submission of investigator-initiated research grant applications in biodefense and emerging infectious diseases To expedite research leading to the prevention, detection, diagnosis, and treatment of diseases caused by potential bioterrorism agents NOTE: FOR DETAILS CONCERNING THE SUBMISSION OF INVESTIGATOR-INITIATED RESEARCH GRANT APPLICATIONS, PLEASE SEE http://www2.niaid.nih.gov/Biodefense/rfalplat.htm BACKGROUND The President's budget for Fiscal Year 2003 for NIAID includes more than $1 billion for research leading to the prevention, detection, diagnosis, and treatment of diseases caused by agents with the potential to be used for the purpose of bioterrorism (see pages 2, 7, and 8 at http://www.nih.gov/news/budgetfy2003/2003NIHpresbudget.pdf). NIAID maintains comprehensive information on its programs in biodefense and emerging infectious diseases at http://www.niaid.nih.gov/publications/bioterrorism.htm. SCOPE OF BIODEFENSE AND EMERGING INFECTIOUS DISEASE PROGRAM The following URLs are links to information on research areas within the scope of NIAID's biodefense and emerging infectious diseases program: o httphttp://www2.niaid.nih.gov/Biodefense/bandc_priority.htm identifies NIAID category A, B and C priority pathogens o http://www2.niaid.nih.gov/Biodefense/Research/high_priority.htm identifies NIAID priority biodefense products o http://www2.niaid.nih.gov/Biodefense/rfalplat.htm identifies NIAID priority research topics and staff contacts BIODEFENSE AND EMERGING INFECTIOUS DISEASES RESEARCH INITIATIVES In addition to investigator-initiated studies, NIAID has active research initiatives in Biodefense and Emerging Infectious Diseases and will be announcing new targeted research initiatives as Requests for Applications, Program Announcements, and Requests for Proposals in the near future. Information about the concepts for future research initiatives is available at: http://www.niaid.nih.gov/ncn/budget/concepts/c-biod0502.htm. Information on all current NIAID initiatives (PAs, RFAs, and RFPs) and on future (Council concept approved) NIAID initiatives can be found at: http://www.niaid.nih.gov/ncn/budget/in-main.htm. INQUIRIES Inquiries are strongly encouraged. Opportunities to clarify any issues or questions from potential applicants are welcome. Based on the area of research, direct inquires regarding scientific, technical and programmatic issues to the appropriate staff member listed here: o Pathogen Replication and Pathogenesis - Viruses: Mark Challberg [email protected] - Genomics: Maria Giovanni [email protected] - Bacteria and fungi: Dennis M. Dixon [email protected] o Epidemiology, natural history and ecology in domestic and/or international sites - Pathogen host interaction: Elizabeth Higgs [email protected] - Reservoirs/vectors: Kate Aultman [email protected] - Zoonoses: Leigh Sawyer [email protected] o Discovery/design and development of vaccines, therapeutics, adjuvants, and diagnostics for biodefense - Therapeutics: Diana Berard [email protected] and Charles Hackett [email protected] - Diagnostics, vaccines, adjuvants: Sonnie Kim [email protected] and Helen Quill [email protected] o Animal Models of Infection and Immunity - Nonviral: Chris Taylor [email protected] - Viruses: Pat Repik [email protected] - Innate immunity and immune evasion: Charles Hackett [email protected] - Adaptive immunity: Helen Quill [email protected] - Genomics and immune responses: Maria Giovanni [email protected] or Alison Deckhut [email protected] - Eczema models: Marshall Plaut [email protected] o Host Response - General immune principles/Immune-related technologies: Alison Deckhut [email protected] - Pathogen specific response: Katherine Taylor [email protected] - Innate immunity Charles Hackett [email protected] - Adaptive immunity: Helen Quill [email protected] Direct inquiries regarding peer review to: Edward W. Schroder, Ph.D. Chief, Microbiology and Immunology Review Branch NIAID Scientific Review Program 6700-B Rockledge Drive MSC 7616 Bethesda, MD 20892-7616 Zip code for express couriers: 20817 Phone: 301-496-2550 FAX: 301-402-2638 Email: [email protected] Direct inquiries regarding fiscal matters to: Lesia Norwood Grants Management Branch National Institute of Allergy and Infectious Diseases National Institutes of Health 6700-B Rockledge Drive, Room 3221, MSC 7610 Bethesda, MD 20892-7610 Phone: (301) 402-6581 Fax: (301) 480-3780 Email: [email protected]
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