Notice of Participation of the National Institute on Aging in PAR-23-285, PAR-23-298, and PAR-23-299
Notice Number:
NOT-AG-24-018

Key Dates

Release Date:

May 30, 2024

Related Announcements

  • September 11, 2023 - Intervention Research to Improve Native American Health (R34 Clinical Trial Optional). See NOFO PAR-23-285
  • September 11, 2023 - Intervention Research to Improve Native American Health (R01 Clinical Trial Optional). See NOFO PAR-23-298
  • September 11, 2023 - Intervention Research to Improve Native American Health (R21 Clinical Trials Optional). See NOFO PAR-23-299

Issued by

National Institute on Aging (NIA)

Purpose

This Notice informs that, effective immediately, the National Institute on Aging (NIA) is participating in the following three (3) NOFOs:

  1. PAR-23-285 - Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)
  2.  PAR-23-298 - Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)
  3.  PAR-23-299 - Intervention Research to Improve Native American Health (R21 Clinical Trials Optional)

To document NIA’s participation, the following sections of the NOFOs were modified:

Part 1. Overview Information 

Components of Participating Organizations

         This section was modified to add:

         National Institute on Aging (NIA)
 

Assistance Listing Number(s)

           This section was modified to add:

           93.866
 

Part 2. Full Text of Announcement

Section I. Funding Opportunity Description

This section was modified to add:

National Institute on Aging (NIA)

NIA supports mechanism-based intervention research to prevent, reduce, or eliminate health disparities and inequities over the life course, especially among older adults and people living with Alzheimer’s disease and Alzheimer’s disease related dementias (AD/ADRD). 

NIA encourages research on factors affecting health and longevity, such as cultural affiliation, socioeconomic and geographic inequality, gender differences, discrimination, and stress, among Native American groups. 

Applicants are encouraged to consider the priorities outlined in NIA’s strategic directions for health disparities research and in the AD+ADRD Research Implementation Milestones related to health disparities. In addition, applicants are strongly encouraged to consider how the proposed activities might be informed by the four key levels of analysis related to health disparities research–environmental, sociocultural, behavioral, and biological—with priority focus areas in each level as reflected within NIA’s Health Disparities framework.

Similarly, NIA encourages applicants to draw upon the NIH Stage Model for Behavioral Intervention Development, which offers a framework to: (1) support development and testing of effective interventions that are defined by their principles and (2) ensure that efficacious interventions can be administered in the community or in health systems with fidelity to the intervention’s principles. This includes the development, testing, and validation of scalable training materials and procedures so that these interventions can be delivered with fidelity in community settings or health systems. In keeping with the Stage Model, applications should propose contemporary analytic techniques to evaluate mechanisms by which the focal intervention impacts health and mitigates health disparities of Native Americans.

Research topics of interests to NIA include, but is not limited to, the following:

  • Understanding mechanisms through which interventions operate that reduce disparate life expectancy, morbidity, or disability among Native American populations.
  • Understanding mechanisms of culturally appropriate interventions to promote cognitive reserve and resilience to AD/ADRD.
  • Structural or institutional interventions that mitigate disparities such as access to health care or services.
  • Development of culturally appropriate interventions that promote holistic health for those living with a serious illness. 
  • Interventions that incorporate traditional healing practices as part of palliative care.
  • Interventions to attenuate the detrimental effects of socio-structural factors and social and environmental determinants of health such as poverty, unemployment, pollution, and poor access to health care in combination with exploring factors such as historical trauma, which may serve to build resiliency and increase healthy life years.
  • Social, cultural, environmental, and behavioral factors over the life course, such as early life adversity, education, employment, health behaviors (e.g., substance use and physical exercise/inactivity), and cultural beliefs, that may influence the effects of interventions on cognitive aging and dementia and explain the link between the aging process and morbidity and mortality. 
  • Strategies that train and utilize community health providers (e.g., public health nurses, community health representatives, behavioral health aides) to reduce symptom burden and improve the quality of life for those experiencing a life-threatening illness and their families.
  • Studies of culturally appropriate prevention and treatment interventions to improve functional and cognitive outcomes in older adults during acute illness and recovery. 
  • Studies of culturally appropriate interventions to improve the health of older women.     

Section VII. Agency Contacts

This section was modified to add:

Scientific/Research Contact(s)

Erin R. Harrell, Ph.D., PMP
Division of Behavioral and Social Research (DBSR)
National Institute on Aging (NIA)
Email: erin.harrell@nih.gov

Frank Bandiera, Ph.D.
Division of Behavioral and Social Research (DBSR)
National Institute on Aging (NIA)
Email: frank.bandiera@nih.gov

Financial/Grants Management Contact(s)

Ryan Blakeney
National Institute on Aging (NIA)
Telephone: 301-451-9802
Email: ryan.blakeney@nih.gov


All other aspects of the NOFO remain the same.

Inquiries

Please direct all inquiries to:

Erin R. Harrell, Ph.D., PMP
Division of Behavioral and Social Research (DBSR)
National Institute on Aging (NIA)
Email: erin.harrell@nih.gov

Frank Bandiera, Ph.D.
Division of Behavioral and Social Research (DBSR)
National Institute on Aging (NIA)
Email: frank.bandiera@nih.gov