August 11, 2022
PA-20-272 - Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
National Institute on Aging (NIA)
The purpose of this Notice of Special Interest (NOSI) is to attract early stage physician-scientists and clinical psychologist-scientists from the U.S. Department of Veterans Affairs (VA) to an Alzheimer’s disease and Alzheimer’s disease-related dementias (AD/ADRD) research career. To accomplish this goal, the VA and the National Institute on Aging (NIA) have created a two-part opportunity for eligible VA applicants to pair with both VA- and NIA-funded mentors in the AD/ADRD field through an IK2 career development award from the VA (described in VA RFAs BX-23-030, CX-23-030, HX-23-030, and RX-23-030) and an administrative supplement from NIA. The research can focus on any aspect of the AD/ADRD field (e.g., disease mechanisms, biomarker discovery, diagnosis/clinical assessment, therapeutics, patient care, community care/social determinants of health, caregiver issues, and models of care). The VA RFAs and NIA NOSI will also promote developing and implementing a collaborative framework to facilitate co-funding and support of shared research priorities between NIA and the VA, enabling increased coordination between the two organizations.
Eligible physician-scientists are defined as those who are no more than 5 years past their last clinical training (e.g., residency, internship, clinical fellowship) and no more than 10 years beyond receipt of their MD or DO degree. If the physician applicants are 10 years past the receipt of their MD or DO degree, they must attach documentation that a waiver was requested and approved with the Letter of Intent (LOI).
Eligible clinical psychologist-scientists are defined as those who possess a doctoral degree and are no more than 5 years past their last clinical training (e.g., internship, clinical fellowship) and no more than 10 years beyond receipt of their PhD degree. If applicants are 10 years past the receipt of their PhD degree, they must attach documentation that a wavier was requested and approved with the Letter of Intent (LOI).
Instructions for requesting an eligibility waiver are provided on page 8 of the VA RFAs BX-23-030, CX-23-030, HX-23-030, and RX-23-030. Waivers are not required for the NIA administrative supplement.
NIA seeks to support research focused on one or more of the following areas:
Application and Submission Process
All instructions in the SF424 (R&R) Application Guide and PA-20-272, "Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)" must be followed, with the following additions:
The IK2 award supported by the VA will provide up to $75,000 per year for clinician salary, travel expenses, and limited support for research supplies.
The NIA administrative supplement solicited by this Notice will support research expenses for conducting the study in the NIA mentor's laboratory (e.g., materials and supplies, support for a technician, post-doc, and/or consultant(s)). Funding can be requested for up to 5 years, with a maximum annual award of $175,000 in direct costs. The project and budget periods must be within the currently approved project period for the existing parent award. It is anticipated that up to 10 awards will be funded. An annual progress report will be required.
Criteria and instructions for administrative supplements are outlined in PA-20-272.
Application and Submission Information
Applications for this initiative must be submitted using the following opportunity or its subsequent reissued equivalent.
Lisa A. Opanashuk, Ph.D.
National Institute on Aging (NIA)