April 16, 2021
RFA-AG-22-016 - Mechanism-Focused Research to Promote Adherence to Healthful Behaviors to Prevent Mild Cognitive Impairment (MCI) and Alzheimer’s Disease and Related Dementias (AD/ADRD) (R61/R33 Clinical Trial Required)
PAR-21-207 - Mechanism-Focused Research to Promote Adherence to Healthful Behaviors to Prevent Mild Cognitive Impairment (MCI) and Alzheimer’s Disease and Related Dementias (AD/ADRD) (R01 Clinical Trial Optional)
National Institute on Aging (NIA)
The purpose of this Notice is to inform potential applicants that the National Institute on Aging (NIA) will hold a pre-application technical assistance live webinar regarding applications for PAR-21-207 and RFA-AG-22-016 on Friday, July 16 at 1:00-2:00PM ET.
PAR-21-207 invites R01 applications for ancillary studies that address psychological and interpersonal mechanisms driving adherence to behavior or lifestyle change relevant to the prevention of cognitive decline, Mild Cognitive Impairment (MCI), and Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD). Successful applications will seek to identify malleable, mechanistic, psychological, or interpersonal targets that – if modified – will strengthen adherence to, maintenance of, and continued/renewed engagement in behaviors that may promote cognitive health and prevent AD/ADRD.
RFA-AG-22-016 invites R61/R33 applications that will identify meaningful (e.g., causal), modifiable factors that promote adherence to lifestyle changes or to other (e.g., cognitive training) behaviors that hold potential for prevention of cognitive decline, MCI, and AD/ADRD. Projects should create, refine, and test early- to late-stage (including Stages I-IV of the NIH Stage Model) interventions that target individual- and interpersonal-level mechanisms of adherence to healthful behavioral patterns and to other prevention approaches for cognitive decline, MCI, and AD/ADRD (e.g., cognitive training). Additionally, this FOA solicits applications for studies that integrate basic science questions of how psychological and interpersonal targets (i.e., processes we can manipulate) and mechanisms may inform the design and development of effective, efficient, and personalized approaches to promote adherence to behavior change for the prevention of AD/ADRD and to help optimize healthy aging over the lifecourse.
The live webinar is part of a collection of applicant resources that have been developed for PAR-21-207 and RFA-AG-22-016. Participants are strongly encouraged to review the recorded technical assistance webinar that describes the purposes and objectives of the announcements as well as the frequently asked questions before attending the live webinar.
The live webinar will address questions submitted by participants prior to and during the webinar. Potential applicants are strongly encouraged to submit questions prior to the webinar to Dr. Luke Stoeckel. Please indicate "PAR-21-207 and RFA-AG-22-016 Webinar" in the subject line of the email. Questions posted during the live session can be submitted through the chat feature.
Potential applicants interested in participating in the webinar should register using this link. Webinar connection information will be provided to registered participants.
The webinar is optional and is not required for submission to the FOA.