EXPIRED
Notice Number: NOT-AG-20-022
Key Dates
Release Date: April 2, 2020
First Available Due Date: April 06, 2020
Expiration Date: May 01, 2021
NOT-OD-21-104- Reminder: Required use of FORMS-F application forms for application submission
Issued by
National Institute of Mental Health (NIMH)
National Institute on Alcohol Abuse and Alcoholism (NIAAA) - New participating organization as of 04/16/2020 for due dates on/after 04/16/2020
Purpose
NIA is issuing this Notice of Special Interest (NOSI) to highlight the urgent need for research on Coronavirus Disease 2019 (COVID-19). The mission of NIA is to support and conduct genetic, biological, clinical, behavioral, social, and economic research on aging. This NOSI supports mission critical areas of research for NIA as they relate to the COVID-19 pandemic.
Background
Coronaviruses are a diverse family of viruses that cause a range of disease in humans and animals, and there are currently no approved coronavirus vaccines or therapeutics. In January 2020, a novel coronavirus, 2019-nCoV, was identified as the causative agent of an outbreak of viral pneumonia centered around Wuhan, China. Current information regarding confirmed cases is changing daily and can be found on the Centers for Disease Control and Prevention website and through other sources such as the NIH website. Transmission characteristics and the associated morbidity and mortality are not completely understood, but there is clear evidence of human-to-human transmission. Many other aspects of viral pathogenesis, natural history, and host range are poorly understood. Given this, there is an urgent public health need to better understand the 2019-nCoV, particularly to improve prevention of disease transmission among older adults and mitigation of disease severity and mortality in older adults with COVID-19.
Research Objectives
In order to rapidly improve our understanding and available control measures for 2019-nCoV, NIA is encouraging the submission of applications for either Administrative Supplements (PA-18-591) or Competitive Revisions (PA-18-935) to active grants to address the following research areas of interest:
Research interests include but are not limited to:
Division of Aging Biology (DAB) Research Interests:
Division of Neuroscience (DN) Research Interests:
Division of Geriatrics and Clinical Gerontology (DGCG) Research Interests:
Division of Behavioral and Social Research (DBSR) Research Interests:
The National Institute of Mental Health (NIMH) will accept and consider support for applications for supplements and revisions to NIMH projects that fall within the scope of this announcement and are relevant to the mission and strategic priorities of the NIMH. Applications to describe the epidemiology of mental disorders and symptoms related to the COVID-19 pandemic are not a high priority; applications to examine how a disrupted workforce may adequately respond/adapt to and maintain services or provide additional care for new or worsening mental health needs and/or suicide risk in midlife and older age adults will be seen as a high priority.
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) will accept either administrative supplements (PA-18-591) or competitive revisions (PA-18-935) to NIAAA-supported projects that fall within the scope of the NOSI NOT-AG-20-022 and are relevant to the mission and strategic priorities of the NIAAA. Specifically, NIAAA is interested in studies that integrate alcohol misuse in research topics outlined in the announcement to better understand, prevent, and mitigate the COVID-19 in older adults who misuse alcohol. NIAAA encourages collaborations between alcohol researchers and experts in aging and dementia research for the proposed projects.
Application and Submission Information
Applications for this initiative must be submitted using the following opportunity or its subsequent reissued equivalent.
Administrative supplement work that is proposed through PA-18-591 Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional) must be within the general scope of the research or training that is already supported. Eligible activity codes for applications to PA-18-591 are limited to the mechanisms listed in PA-18-591.
Applications that involve a change in scope (e.g., the addition of human subjects to a grant that has not been previously so coded and approved, the addition of vertebrate animals to a grant that has not been previously so coded and approved) must apply through PA-18-935 Urgent Competitive Revision to Existing NIH Grants and Cooperative Agreements (Urgent Supplement - Clinical Trial Optional). Eligible activity codes for applications to PA-18-935 are limited to the following mechanisms: P01, P30, RF1, R00, R01, R03, R15, R21, R24, R25, R33, R35, R41, R42, R43, R44, R56, R61, U01, U19, U24, U54, UG3, UH3, UM1, K01, K02, K07, K08, K23, K24, K25,K76.
To be eligible for either an Administrative Supplement or Urgent Competitive Revision, the parent award on which the supplement or revision application is based must be an active NIA, NIMH or NIAAA award (i.e., not be in an extension period) at the time the supplement or revision is awarded.
NIAAA : Application budgets are generally limited to no more than $100,000 direct costs per year. Should the proposed research require a higher budget, the applicant should consult with the program official assigned to the parent award. Permission to exceed $100,000 must be acquired from NIAAA’s Office of Extramural Activities prior to submission. The PI must include a strong justification for the larger budget in the supplement application. The proposed budget must reflect the actual needs of the proposed project.
All instructions in the SF424 (R&R) Application Guide and PA-18-591 must be followed, with the following additions:
Investigators planning to submit an application in response to this NOSI are strongly encouraged to contact and discuss their proposed research/aims with program staff listed below well in advance of the grant receipt date to better determine appropriateness and interest of the NIA.
Inquiries
Please direct all inquiries to:
Scientific/Research Contact(s)
Division of Aging Biology (DAB) Contact:
Rebecca Fuldner, Ph.D.
National Institute on Aging (NIA)
Telephone: 301-402-7748
Email: fuldnerr@nia.nih.gov
Division of Neuroscience (DN) Contact:
Miroslaw Mackiewicz, Ph.D.
National Institute on Aging (NIA)
Telephone: 301-594-7636
Email: miroslaw.mackiewicz@nih.gov
Division of Geriatrics and Clinical Gerontology (DGCG) Contact:
Basil A. Eldadah, MD, Ph.D.
National Institute on Aging (NIA)
Telephone: 301-496-6761
Email: eldadahb@nia.nih.gov
Division of Behavioral and Social Research (DBSR) Contact:
John Phillips, Ph.D.
National Institute on Aging (NIA)
Telephone: 301-827-4137
Email: john.phillips@nih.gov
Susan Borja, Ph.D.
National Institute of Mental Health (NIMH)
Telephone: 310-443-1252
Email: susan.borja@nih.gov
Changhai Cui, Ph.D.
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Telephone: 301-443-1678
Email: Changhai.cui@nih.gov
Financial/Grants Management Contact
Traci Lafferty
National Institute on Aging (NIA)
Telephone: 301-496-8987
laffertt@nia.nih.gov
Rita Sisco
National Institute of Mental Health (NIMH)
Telephone: 301-443-2805
Email: siscor@mail.nih.gov
Jeff Thurston
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Phone: 301-443-9801
Email: jeffrey.thurston@nih.gov