Notice Number: NOT-AG-18-005

Key Dates
Release Date: March 21, 2018

Issued by
National Institute on Aging (NIA)

Purpose

The purpose of this Notice is to inform potential applicants that the National Institute on Aging (NIA) is participating in PA-18-343, "Academic Research Enhancement Award (R15 Clinical Trial Required)."

The following changes have been made to reflect NIA's participation in this FOA:

Part 1. Overview Information

The following text has been added:

Components of Participating Organizations
National Institute on Aging (NIA)
Catalog of Federal Domestic Assistance (CFDA) Number(s)
93.866

Part 2. Section I. Funding Opportunity Description

The following text has been added:

National Institute on Aging (NIA)

The National Institute on Aging (NIA) is interested in supporting clinical trials related to the promotion of healthy aging and the wellbeing of older adults. Examples of relevant topics include, but are not limited to, interventions that aim to:

• Prevent, delay, or improve age-related cognitive decline, cognitive impairment, and/or Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD)
• Prevent or treat behavioral (agitation, anxiety, depression, etc.) symptoms associated with Alzheimer's disease and/or ADRD
• Improve outcomes for persons with dementia and caregivers in formal and informal settings
• Translate existing clinical guidelines into new and effective tools for the clinical care and management of Alzheimer’s Disease, ADRD, and their comorbidities.
• Increase physical activity and improve diet
• Use information technology to improve quality of life
• Reduce fall risk and improve balance, gait and mobility (biomechanics)
• Enhance access to and quality of health services
• Remediate sensory and/or motor impairments in older adults
• Prevent or treat delirium or post-operative cognitive decline in older adults
• Test the effectiveness of self-management interventions for multiple chronic conditions to reduce burden and disability, improve well-being, strengthen participation in health care, and/or prevent illness and complications in varied clinical and/or community settings
• Develop patient-focused tools for prioritizing and making decisions about the most significant health concerns to help select and order self -management behaviors related to multiple chronic conditions.
• Develop techniques for preventing or treating urinary incontinence
• Prevent, delay, or improve age-related issues related to physical function, frailty, sarcopenia and other musculoskeletal issues
• Improve management of pain/palliative Care
• Enhance healthy aging (i.e. slows rates of aging changes) through nutritional or other lifestyle modifications
• Repurpose FDA approved drugs/molecules for modulating aging pathways and enhance health span

Part 2. Section VII. Agency Contacts

The following text has been added:

Scientific/Research Contact(s):
Jonathan W. King, Ph.D.
National Institute on Aging (NIA)
Telephone: 301-496-3136
Email: [email protected]

Financial/Grants Management Contact(s):
Jillian Morris
National Institute on Aging (NIA)
Telephone: 301-496-8986
Email: [email protected]

Inquiries

Please direct all inquiries to:

Jonathan W. King, Ph.D.
National Institute on Aging (NIA)
Telephone: 301-496-3136
Email: [email protected]