Notice Number: NOT-AG-12-014

Key Dates
Release Date: August 6, 2012

Issued by
National Institute on Aging (NIA)

Purpose

This Notice is to inform applicants that NIA has joined the National Institute of Arthritis and Musculoskeletal and Skin Diseases entitled "Functions of Skeletal Muscle Beyond Contraction" (PA-12-208) and encourages R01 applications for support of innovative, exploratory/developmental projects aimed at studying the effects, mechanisms and influence of aging on the spectrum of activities of skeletal muscle in health and disease that are beyond its classical role in contraction and locomotion. These activities include endocrine and paracrine functions of skeletal muscle, resting muscle thermogenesis, sensing of biomechanical stimuli, storing amino acids, regulating systemic metabolism, etc. Advancing understanding of the role of aging in these important functions of muscle may lead to novel strategies for the prevention or treatment of common conditions such as cachexia, obesity, diabetes and sarcopenia.

Components of Participating Organizations
The Components of Participating Organizations section of PA-12-208, (R01) has been revised to include NIA:

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute on Aging (NIA)

Catalog of Federal Domestic Assistance Numbers
93.846 National Institute of Arthritis and Musculoskeletal and Skin Diseases
93.866 National Institute on Aging

Inquiries

Please direct all inquiries to:

John P Williams, Ph.D.
Director Musculoskeletal Biology Program
Division of Aging Biology
National Institute on Aging
7201 Wisconsin Ave
Bethesda, MD 20892
Telephone: (301) 496-6403
FAX: (301) 410-0010
Email: [email protected]